Targeting cellular senescence with senotherapeutics: senolytics and senomorphics

L Zhang, LE Pitcher, V Prahalad… - The FEBS …, 2023 - Wiley Online Library
The concept of geroscience is that since ageing is the greatest risk factor for many diseases
and conditions, targeting the ageing process itself will have the greatest impact on human …

Plant phenolics: Bioavailability as a key determinant of their potential health-promoting applications

P Cosme, AB Rodríguez, J Espino, M Garrido - Antioxidants, 2020 - mdpi.com
Phenolic compounds are secondary metabolites widely spread throughout the plant
kingdom that can be categorized as flavonoids and non-flavonoids. Interest in phenolic …

Stilbenes: Source plants, chemistry, biosynthesis, pharmacology, application and problems related to their clinical Application-A comprehensive review

T Teka, L Zhang, X Ge, Y Li, L Han, X Yan - Phytochemistry, 2022 - Elsevier
Stilbenes are some of the important phenolic compounds originating from plant families like
Vitaceae, Leguminaceae, Gnetaceae, and Dipterocarpaceae. Structurally, they have a C6 …

Mediterranean diet as an antioxidant: the impact on metabolic health and overall wellbeing

KV Gantenbein, C Kanaka-Gantenbein - Nutrients, 2021 - mdpi.com
It has been established, worldwide, that non-communicable diseases such as obesity,
diabetes, metabolic syndrome, and cardiovascular events account for a high percentage of …

Anti-obesity effects of polyphenol intake: Current status and future possibilities

M Boccellino, S D'Angelo - International journal of molecular sciences, 2020 - mdpi.com
The prevalence of obesity has steadily increased worldwide over the past three decades.
The conventional approaches to prevent or treat this syndrome and its associated …

Benefits and implications of resveratrol supplementation on microbiota modulations: a systematic review of the literature

AD Inchingolo, G Malcangi, AM Inchingolo… - International Journal of …, 2022 - mdpi.com
Resveratrol is a polyphenol that has been shown to possess many applications in different
fields of medicine. This systematic review has drawn attention to the axis between …

Biochemical and cellular basis of oxidative stress: implications for disease onset

K Aramouni, R Assaf, A Shaito… - Journal of Cellular …, 2023 - Wiley Online Library
Cellular oxidation–reduction (redox) systems, which encompass pro‐and antioxidant
molecules, are integral components of a plethora of essential cellular processes. Any …

Resveratrol and immune cells: a link to improve human health

A Alesci, N Nicosia, A Fumia, F Giorgianni, A Santini… - Molecules, 2022 - mdpi.com
The use of polyphenols as adjuvants in lowering risk factors for various debilitating diseases
has been investigated in recent years due to their possible antioxidant action. Polyphenols …

Biological function of resveratrol and its application in animal production: a review

Q Meng, J Li, C Wang, A Shan - Journal of Animal Science and …, 2023 - Springer
With the prohibition of antibiotics in feed, plant functional substances have been widely
studied as feed additives. Resveratrol, a natural stilbene, and a non-flavonoid polyphenol …

Plant polyphenols and their potential benefits on cardiovascular health: A review

I Iqbal, P Wilairatana, F Saqib, B Nasir, M Wahid… - Molecules, 2023 - mdpi.com
Fruits, vegetables, and other food items contain phytochemicals or secondary metabolites
which may be considered non-essential nutrients but have medicinal importance. These …