The applications of epigallocatechin gallate (EGCG)-nanogold conjugate in cancer therapy

M Karimi-Shahri, A Alalikhan, P Hashemian… - …, 2023 - iopscience.iop.org
Cancer has recently increased the death toll worldwide owing to inadequate therapy and
decreased drug bioavailability. Long-term and untargeted chemotherapeutic exposure …

Histopathological Evaluation of Annona muricata in TAA-Induced Liver Injury in Rats

MH Al-Medhtiy, AA Jabbar, SH Shareef, IAA Ibrahim… - Processes, 2022 - mdpi.com
This research in vivo assessed the impact of the ethanolic extract of Annona muricata (A.
muricata) on the histopathology, immunohistochemistry, and biochemistry of thioacetamide …

Sinapic acid attenuate liver injury by modulating antioxidant activity and inflammatory cytokines in thioacetamide-induced liver cirrhosis in rats

AAJ Jabbar, ZZ Alamri, MA Abdulla, AS AlRashdi… - Biomedicines, 2023 - mdpi.com
Sinapic acid (SA) is a natural pharmacological active compound found in berries, nuts, and
cereals. The current study aimed to investigate the protective effects of SA against …

[HTML][HTML] Hepatoprotective effect of pinostrobin against thioacetamide-induced liver cirrhosis in rats

SH Shareef, MH Al-Medhtiy, AS Al Rashdi… - Saudi Journal of …, 2023 - Elsevier
The study in vivo assessed the effect of pinostrobin on the histology, immunohistochemistry,
and biochemical parameters of thioacetamide (TAA) induced liver cirrhosis in Sprague …

A patent review on HMGB1 inhibitors for the treatment of liver diseases

R Raj, P Shen, B Yu, J Zhang - Expert Opinion on Therapeutic …, 2024 - Taylor & Francis
Introduction HMGB1 is a non-histone chromatin protein released or secreted in response to
tissue damage or infection. Extracellular HMGB1, as a crucial immunomodulatory factor …

Evaluation of the effect of wheat germ oil and olmutinib on the thioacetamide-induced liver and kidney toxicity in mice

S Alamery, S Zargar, F Yaseen, TA Wani, A Siyal - Life, 2022 - mdpi.com
Thioacetamide (TAA) intoxication produces a reproducible standard animal model of
induced liver and kidney injuries where free radicals are produced by phase I oxidation …

Hepatoprotective effect of alpinetin on thioacetamide-induced liver fibrosis in sprague dawley rat

SH Shareef, ASM Juma, DNF Agha, AR Alzahrani… - Applied Sciences, 2023 - mdpi.com
Alpinetin is an original medicinal plant flavonoid derived from Alpinia katsumadai and has
several biological activities. The current research aimed to evaluate the hepatoprotective …

Natural products for migraine: Data-mining analyses of Chinese Medicine classical literature

CS Zhang, S Lyu, AL Zhang, X Guo, J Sun… - Frontiers in …, 2022 - frontiersin.org
Background: Treatment effect of current pharmacotherapies for migraine is unsatisfying.
Discovering new anti-migraine natural products and nutraceuticals from large collections of …

Hepatoprotective activity of Lactéol® forte and quercetin dihydrate against thioacetamide‐induced hepatic cirrhosis in male albino rats

HM Saad, SS Oda, A Alexiou… - Journal of Cellular …, 2024 - Wiley Online Library
Liver cirrhosis is a silent disease in humans and is experimentally induced by many drugs
and toxins as thioacetamide (TAA) in particular, which is the typical model for experimental …

Gastro-Protective and Therapeutic Effect of Punica granatum against Stomach Ulcer Caused by Helicobacter Pylori

AJ Muhialdin, ZZ Alamri, AM Hussein… - Cellular and Molecular …, 2023 - cellmolbiol.org
Gastric ulcer is a chronic condition that occurs when the mucosa of the stomach is broken.
There is a physiological equilibrium between aggressive factors and mucosal defense. The …