Doxorubicin (Dox) is a secondary metabolite of the mutated strain of Streptomyces peucetius
var. Caesius and belongs to the anthracyclines family. The anti-cancer activity of Dox is …

Doxorubicin is utilized for anti-neoplastic treatment for several decades. The utility of this
drug is limited due to its side effects. Generally, doxorubicin toxicity is originated from the …

Doxorubicin (DOX) is a potent anti-cancer agent that has garnered great interest in research
due to its high efficacy despite dose-limiting toxicities. Several strategies have been …

After a reperfused myocardial infarction (MI), dynamic tissue changes occur (edema,
inflammation, microvascular obstruction, hemorrhage, cardiomyocyte necrosis, and …

Doxorubicin (DOX) is one of the most effective anticancer drugs to treat various forms of
cancers; however, its therapeutic utility is severely limited by its associated cardiotoxicity …

The incidence and mortality of various cancers are associated with sex-specific disparities.
Sex differences in cancer epidemiology are one of the most significant findings. Men are …

Anthracyclines, such as doxorubicin, are effective chemotherapeutic agents for the treatment
of cancer, but their clinical use is associated with severe and potentially life-threatening …

Doxorubicin is an anthracycline and one of the more effective chemotherapy agents used in
the treatment of children, adolescents, and adults with osteosarcoma. Despite its …

Background: Anthracycline-induced cardiotoxicity is a major clinical problem, and early
cardiotoxicity markers are needed. Objectives: The purpose of this study was to identify early …

Doxorubicin is a widely used and promising anticancer drug; however, a severe dose-
dependent cardiotoxicity hampers its therapeutic value. Doxorubicin may cause acute and …