Guidelines for diagnosis, treatment, and prevention ofclostridium difficileInfections

CM Surawicz, LJ Brandt, DG Binion… - Official journal of the …, 2013 - journals.lww.com
Clostridium difficileinfection (CDI) is a leading cause of hospital-associated gastrointestinal
illness and places a high burden on our health-care system. Patients with CDI typically have …

Risk Factors for Recurrence, Complications and Mortality in Clostridium difficile Infection: A Systematic Review

CN Abou Chakra, J Pepin, S Sirard, L Valiquette - PloS one, 2014 - journals.plos.org
Background Clostridium difficile infection (CDI) can lead to complications, recurrence, and
death. Numerous studies have assessed risk factors for these unfavourable outcomes, but …

Randomised clinical trial: faecal microbiota transplantation by colonoscopy vs. vancomycin for the treatment of recurrent Clostridium difficile infection

G Cammarota, L Masucci, G Ianiro… - Alimentary …, 2015 - Wiley Online Library
Background Faecal microbiota transplantation (FMT) from healthy donors is considered an
effective treatment against recurrent Clostridium difficile infection. Aim To study the effect of …

Derivation and validation of a simple clinical bedside score (ATLAS) for Clostridium difficile infection which predicts response to therapy

MA Miller, T Louie, K Mullane, K Weiss, A Lentnek… - BMC infectious …, 2013 - Springer
Background Clostridium difficile infection (CDI) continues to be a frequent and potentially
severe infection. There is currently no validated clinical tool for use at the time of CDI …

Mortality Following Clostridioides difficile Infection in Europe: A Retrospective Multicenter Case-Control Study

J Czepiel, M Krutova, A Mizrahi, N Khanafer, DA Enoch… - Antibiotics, 2021 - mdpi.com
We aimed to describe the clinical presentation, treatment, outcome and report on factors
associated with mortality over a 90-day period in Clostridioides difficile infection (CDI) …

Comparison of clinical severity score indices for Clostridium difficile infection

S Fujitani, WL George, AR Murthy - Infection Control & Hospital …, 2011 - cambridge.org
Objective. To compare 8 severity score indices for Clostridium difficile infection (CDI).
Design. Prospective observational study. Methods. This study was conducted from July …

Proton pump inhibitors as a risk factor for paediatric Clostridium difficile infection

R Turco, M Martinelli, E Miele… - Alimentary …, 2010 - Wiley Online Library
Aliment Pharmacol Ther 31, 754–759 Summary Background Proton pump inhibitors (PPIs)
and H2 receptor antagonists (H2RAs) may play an important role on the onset of Clostridium …

The appendix may protect against Clostridium difficile recurrence

GY Im, RJ Modayil, CT Lin, SJ Geier, DS Katz… - Clinical …, 2011 - Elsevier
BACKGROUND & AIMS: Several risk factors have been identified for the development of
recurrent Clostridium difficile infection (CDI) that alter host immunity and disrupt colonic flora …

Prediction Tools for Unfavourable Outcomes in Clostridium difficile Infection: A Systematic Review

CN Abou Chakra, J Pepin, L Valiquette - PloS one, 2012 - journals.plos.org
Context Identifying patients at risk for adverse outcomes of Clostridium difficile infection
(CDI), including recurrence and death, will become increasingly important as novel …

Predictors of severe outcomes associated with Clostridium difficile infection in patients with inflammatory bowel disease

AN Ananthakrishnan, R Guzman‐Perez… - Alimentary …, 2012 - Wiley Online Library
Background The increasing incidence of Clostridium difficile (C. difficile) infection (CDI)
among patients with inflammatory bowel disease is well recognised. However, most studies …