In therapeutic cancer vaccines, vaccine antigens must be efficiently delivered to the antigen-
presenting cells (dendritic cells and macrophages) located in the lymphoid organs (lymph …

The vitamin, folic acid, has become a useful ligand for targeted cancer therapies because it
binds to a tumor-associated antigen known as the folate receptor (FR). By linking folic acid to …

Cancer cells can induce an immunological response resulting in the production of tumor-
associated (TA) autoantibodies. These serum immunobiomarkers have been detected for a …

Radiation therapy is currently one of the most widely utilized treatment strategies in the
clinical management of cancer. Classically, radiation therapy was developed as an …

Cancer is a disease of altered signaling and metabolism, causing uncontrolled division and
survival of transformed cells. A host of molecules, factors, and conditions have been …

Dendritic cells (DCs) can be utilized either as vectors or as targets for therapy. Patients with
metastatic melanoma received CD34‐DC vaccine that contains Langerhans' cells and …

The complex of humoral factors and immune cells comprises two interleaved systems,
innate and acquired. Immune cells scan the occurrence of any molecule that it considers to …

The cell surface receptor for the vitamin folic acid (termed the folate receptor), is often
elevated in cancers of the ovary, kidney, lung, mammary gland, brain, endometrium, and …

Nanocarriers passively accumulate in solid tumors through irregular wide fenestrations in
neovasculature and increased retention due to poor lymphatic drainage, a phenomenon …

Lung cancer remains the leading common cause of cancer-related death, with non-small-
cell lung cancer (NSCLC) accounting for 80% of all cases. To date, platinum-based doublet …