Mesoporous silica nanoparticles doped with gold nanoparticles for combined cancer immunotherapy and photothermal therapy
Cancer immunotherapy is a treatment that utilizes the host immune system to fight against
cancer. Inducing a cancer antigen-specific adaptive immune response is key in cancer …
cancer. Inducing a cancer antigen-specific adaptive immune response is key in cancer …
[HTML][HTML] Laminarin promotes anti-cancer immunity by the maturation of dendritic cells
This research evaluates the effects of laminarin on the maturation of dendritic cells and on
the in vivo activation of anti-cancer immunity. In vivo treatment of C56BL/6 mice with …
the in vivo activation of anti-cancer immunity. In vivo treatment of C56BL/6 mice with …
Tuning tumor-specific T-cell activation: a matter of costimulation?
H Abken, A Hombach, C Heuser, K Kronfeld… - Trends in …, 2002 - cell.com
The stimulation of a specific antitumor immune response, involving the recruitment of T cells
and induction of T-cell effector functions, is an attractive possibility for cancer …
and induction of T-cell effector functions, is an attractive possibility for cancer …
[HTML][HTML] Purified human anti-Tn and anti-T antibodies specifically recognize carcinoma tissues
N Zlocowski, V Grupe, YC Garay, GA Nores… - Scientific Reports, 2019 - nature.com
Described in several epithelial cancer cells, Tn-(GalNAcα1-O-Ser/Thr) and T-
(Galβ3GalNAcα1-O-Ser/Thr) antigens are examples of tumor-associated antigens …
(Galβ3GalNAcα1-O-Ser/Thr) antigens are examples of tumor-associated antigens …
[HTML][HTML] The confluence of radiotherapy and immunotherapy
B Burnette, YX Fu, RR Weichselbaum - Frontiers in oncology, 2012 - frontiersin.org
Radiotherapy (RT) has been considered a local modality and outcomes have emphasized
local and regional control of tumors. Recent data suggests that RT may activate the immune …
local and regional control of tumors. Recent data suggests that RT may activate the immune …
[HTML][HTML] Recombinant AAV-CEA tumor vaccine in combination with an immune adjuvant breaks tolerance and provides protective immunity
JA Hensel, V Khattar, S Ponnazhagan - Molecular Therapy-Oncolytics, 2019 - cell.com
Carcinoembryonic antigen (CEA) is a human glycoprotein involved in cellular adhesion and
expressed during human fetal development. Although expression of CEA largely ceases …
expressed during human fetal development. Although expression of CEA largely ceases …
Ex vivo characterization of tumor-derived melanoma antigen encoding gene-specific CD8+ cells in patients with hepatocellular carcinoma
A Zerbini, M Pilli, P Soliani, S Ziegler, G Pelosi… - Journal of …, 2004 - Elsevier
Background/Aims: Members of the melanoma antigen encoding gene family are expressed
in tumors of different histological types but not in normal tissue. For this reason, they are …
in tumors of different histological types but not in normal tissue. For this reason, they are …
Cancer-testis antigens: promising targets for antigen directed antineoplastic immunotherapy
B Bodey - Expert opinion on biological therapy, 2002 - Taylor & Francis
During the last decade, the aberrant expression of normal testicular proteins in
neoplastically transformed cells became common knowledge. Cancer-testis antigens (CTAs) …
neoplastically transformed cells became common knowledge. Cancer-testis antigens (CTAs) …
[HTML][HTML] Functional and structural characteristics of NY-ESO-1-related HLA A2-restricted epitopes and the design of a novel immunogenic analogue
NY-ESO-1, a commonly expressed tumor antigen of the cancer-testis family, is expressed by
a wide range of tumors but not found in normal adult somatic tissue, making it an ideal …
a wide range of tumors but not found in normal adult somatic tissue, making it an ideal …
NY‐ESO‐1 protein expression in primary breast carcinoma and metastases—correlation with CD8+ T‐cell and CD79a+ plasmacytic/B‐cell infiltration
JP Theurillat, F Ingold, C Frei… - … journal of cancer, 2007 - Wiley Online Library
NY‐ESO‐1 is a cancer testis antigen expressed in various malignancies and testicular germ
cells. Because of its capacity to induce specific humoral and cellular immunity in patients …
cells. Because of its capacity to induce specific humoral and cellular immunity in patients …