Purpose: Hepatocellular carcinoma (HCC) can express various cancer-testis antigens
including NY-ESO-1, members of the SSX family, members of the MAGE family, SCP-1, and …

BACKGROUND Prostate cancer (PC) is the second most common cancer in older men, after
skin cancer. PC is difficult to diagnose because the prostate‐specific antigen screening …

Boron neutron capture therapy (BNCT) has been used both experimentally and clinically for
the treatment of gliomas and melanomas, with varying results. However, the therapeutic …

The tumor specific antigen epitope melanoma antigen A1161–169 (MAGE-A1161–169) was
displayed on the major protein (pVIII) of the filamentous bacteriophage (fd). The immune …

Our previous study demonstrated that ascophyllan, a sulfated polysaccharide purified from
brown alga, has immune-activating effects. In this study, we evaluated ascophyllan as an …

In the 1990s, the application of immunotherapy approaches to target cancer cells resulted in
significant clinical responses in patients with advanced malignancies who were refractory to …

To meet the ultimate goal of cancer therapy, which is treating not only the primary tumor but
also preventing metastatic cancer, the concept of combining immunotherapy with …

New York esophageal squamous cell carcinoma-1 (NY-ESO-1), a cancer testis antigen, is
an ideal target for adoptive cell transfer immunotherapy. Evidence from several clinical trials …

FATE and TPTE genes were originally reported to be specifically expressed in the adult
testis. We searched for the databases of Unigene and serial analysis of gene expression …

Eleven years have passed since the start of the first trial of dendritic cell (DC) vaccination for
melanoma. A review of 54 trials was performed to evaluate the relationship between clinical …