[HTML][HTML] Frontotemporal dementia, where do we stand? A narrative review

A Antonioni, EM Raho, P Lopriore, AP Pace… - International journal of …, 2023 - mdpi.com
Frontotemporal dementia (FTD) is a neurodegenerative disease of growing interest, since it
accounts for up to 10% of middle-age-onset dementias and entails a social, economic, and …

[HTML][HTML] Cellular metabolism: A fundamental component of degeneration in the nervous system

K Maiese - Biomolecules, 2023 - mdpi.com
It is estimated that, at minimum, 500 million individuals suffer from cellular metabolic
dysfunction, such as diabetes mellitus (DM), throughout the world. Even more concerning is …

[HTML][HTML] Cognitive impairment in multiple sclerosis

K Maiese - Bioengineering, 2023 - mdpi.com
Almost three million individuals suffer from multiple sclerosis (MS) throughout the world, a
demyelinating disease in the nervous system with increased prevalence over the last five …

Co-ultramicronized palmitoylethanolamide/luteolin normalizes GABAB-ergic activity and cortical plasticity in long COVID-19 syndrome

V Versace, P Ortelli, S Dezi, D Ferrazzoli… - Clinical …, 2023 - Elsevier
Objective Transcranial magnetic stimulation (TMS) studies showed that patients with
cognitive dysfunction and fatigue after COVID-19 exhibit impaired cortical GABA B-ergic …

[HTML][HTML] The impact of aging and oxidative stress in metabolic and nervous system disorders: programmed cell death and molecular signal transduction crosstalk

K Maiese - Frontiers in immunology, 2023 - frontiersin.org
Life expectancy is increasing throughout the world and coincides with a rise in non-
communicable diseases (NCDs), especially for metabolic disease that includes diabetes …

[HTML][HTML] Ether lipid-mediated antioxidant defense in Alzheimer's disease

M Jové, N Mota-Martorell, È Obis, J Sol, M Martín-Garí… - Antioxidants, 2023 - mdpi.com
One of the richest tissues in lipid content and diversity of the human body is the brain. The
human brain is constitutively highly vulnerable to oxidative stress. This oxidative stress is a …

[HTML][HTML] Curcumae radix Reduces Endoplasmic Reticulum Stress in Mice with Chronic Neuroinflammation

SL Jo, H Yang, HW Lee, EJ Hong - Biomedicines, 2023 - mdpi.com
Endoplasmic reticulum (ER) stress is a condition in which the ER protein-folding machinery
is impaired, leading to the accumulation of improperly folded proteins and triggering an …

Clinical Depression, the Mechanistic Target of Rapamycin (mTOR), and Forkhead Transcription Factors (FoxOs)

K Maiese - Current Neurovascular Research, 2023 - ingentaconnect.com
Depression is a disorder in the mental health of an individual that leads to a low level of
activity and feelings of despair and hopelessness [1-3]. Depression can lead to the inability …

[HTML][HTML] Therapeutic potential of clinically proven natural products in the management of dementia

F Ansari, M Sohel, MMH Haidary, MS Mostaq, S Akter… - Heliyon, 2024 - cell.com
Dementia is a common neurodegenerative disorder connected to damage to nerve cells in
the brain. Although some conventional drugs are available for dementia treatments and are …

A decades-long journey of palmitoylethanolamide (PEA), as a cornerstone in chronic neuropathic pain management: a comprehensive narrative review

G Varrassi, A Paladini, C Corno, S Coaccioli, G Finco… - 2024 - preprints.org
Palmitoylethanolamide (PEA) has been prescribed for neuropathic pain for several years.
This study is mainly addressed to summarize what has been published on the topic in the …