In silico and in vitro exploration of poziotinib and olmutinib synergy in lung cancer: role of hsa-miR-7-5p in regulating apoptotic pathway marker genes
Background and objectives: Non-small cell lung cancer (NSCLC) is often caused by EGFR
mutations, leading to overactive cell growth pathways. Drug resistance is a significant …
mutations, leading to overactive cell growth pathways. Drug resistance is a significant …
[HTML][HTML] Natural products modulate phthalate-associated miRNAs and targets
YT Chuang, CY Yen, TM Chien, FR Chang… - Ecotoxicology and …, 2024 - Elsevier
Phthalates are widespread and commonly used plasticizers that lead to adverse health
effects. Several natural products provide a protective effect against phthalates. Moreover …
effects. Several natural products provide a protective effect against phthalates. Moreover …
The binding selectivity of quercetin and its structure-related polyphenols to human serum albumin using a fluorescent dye cocktail for multiplex drug-site mapping
R Mukai, H Okuyama, M Uchimura, K Sakao… - Bioorganic …, 2024 - Elsevier
Human serum albumin (HSA) is a serum protein that carries flavonoids in blood circulation.
In this report, the binding selectivity and strength of interactions to HSA-binding sites (sites I …
In this report, the binding selectivity and strength of interactions to HSA-binding sites (sites I …
Uncovering the anti-breast cancer activity potential of east Kalimantan propolis by In vitro and bioinformatics analysis
Numerous side effects of breast cancer drugs have prompted researchers to explore more
into new therapeutic approaches derived from natural substances. In this context, our study …
into new therapeutic approaches derived from natural substances. In this context, our study …
Strategic development and validation of Isoquinoline-Derived inhibitors targeting ROCK1 kinase
P Hu, QX Xu, Y Wang, JH Hua, GM Yang… - Journal of Molecular …, 2024 - Elsevier
Rho-associated coiled-coil containing kinases (ROCKs) have emerged as pivotal
downstream effectors of small guanosine triphosphatases. In recent years, isoquinoline …
downstream effectors of small guanosine triphosphatases. In recent years, isoquinoline …
Computational molecular perspectives on novel carbazole derivative as an anti-cancer molecule against CDK1 of breast and colorectal cancers via gene expression …
E Suvarna, AS Setlur, K Chandrashekar… - … Biology and Chemistry, 2024 - Elsevier
With increase in cancer incidences, alternative strategies for disease management are of
utmost importance. Carbazole, is a compound that is being studied extensively as an anti …
utmost importance. Carbazole, is a compound that is being studied extensively as an anti …
[HTML][HTML] Quercetin: A Flavonoid with Diverse Chemo Preventive Properties against Cancer
MI Rushdi - Quercetin-Effects on Human Health, 2024 - intechopen.com
Quercetin, an exceptional and extraordinary flavonoid possessing bioactive properties,
presents a plethora of benefits for the promotion of good health. The anti-tumor …
presents a plethora of benefits for the promotion of good health. The anti-tumor …