In crossing a heath, suppose... I had found a watch upon the ground, and it should be
inquired how the watch happened to be in that place....[T] he inference, we think, is …

The surface of a cell represents a collection of macromolecules, which provides the cell with
a unique cellular landscape specific to the type and state of the cell. Ligands that …

Since its first description in 1985, publications involving phage display have relied upon the
fact that the displayed entity, be it a peptide, protein, or antibody fragment, is physically …

Antigenic epitopes are the part (contact points) of an antigen involved in specific interaction
with the antigen-binding site (the paratope) of an antibody or a T-cell receptor. Detailed …

The vast majority of anti-infective therapeutics on the market or in development are small
molecules; however, there is now a nascent pipeline of biological agents in development …

T cell independent antigens do not require T cell help to induce an immune response, and
are characterized by a lack of immunologic memory. These antigens can be divided into two …

For the past 25 years, phage display technology has been an invaluable tool for studies of
protein–protein interactions. However, the inherent biological, biochemical, and biophysical …

The structural requirements for peptide binding to an antibody may be elucidated by probing
it with a variety of peptides having different constraints. To this end, we have constructed and …

Chlamydiae are obligate intracellular bacterial pathogens of eukaryotic cells responsible for
a wide variety of important human and animal infections. In humans, chlamydial infections …

Au cours des 7 années qui ont suivi les premières publications décrivant des banques de
peptides exposés à la surface de phages, cet affichage d'un phage a été utilisé avec succès …