Fatty acid acylation of proteins is a well-studied co-or posttranslational modification typically
conferring membrane trafficking signals or membrane anchoring properties to proteins …

Until recently, the lens was thought to express only two aquaporin (AQP) water channels,
AQP1 and AQP0. In this study we confirm lenticular AQP5 protein expression by Western …

Tissue development and regeneration involve high-ordered morphogenetic processes that
are governed by elements of the cytoskeleton in conjunction with cell adhesion molecules …

Purpose.: Lens fiber cell membranes contain aquaporin-0 (AQP0), which constitutes
approximately 50% of the total fiber cell membrane proteins and has a dual function as a …

Membrane proteins are abundant, critically important biomolecules that conduct essential
functions in all cells and are the targets of a significant number of therapeutic drugs …

Congenital cataracts are the leading cause of irreversible visual disability in children, and
genetic factors play an important role in their development. In this study, targeted exome …

Transport of water is critical for maintaining the transparency of the avascular lens, and the
lens is known to express at least five distinctly different water channels from the Aquaporin …

Abstract Aquaporin 0 (AQP0) is a transmembrane channel that constitutes∼ 45% of the total
membrane protein of the fiber cells in mammalian lens. It is critical for lens transparency and …

The Drosophila Dpr and DIP proteins belong to the immunoglobulin superfamily of cell
surface proteins (CSPs). Their hetero-and homophilic interactions have been implicated in a …

On the basis of recent advances in molecular biology, genetics, and live-embryo imaging,
direct comparisons between zebra fish and human lens development are being made. The …