The scope of this investigation was to understand the role of aquaporin 5 (AQP5) for
maintaining lens transparency and homeostasis. Studies were conducted using lenses of …

Aquaporin (AQP) 1 and AQP0 water channels are expressed in lens epithelial and fiber
cells, respectively, facilitating fluid circulation for nourishing the avascular lens to maintain …

Fluid homeostasis is recognized as a critical factor during the development, maturation, and
function of vertebrate male germ cells. These processes have been associated with the …

The Drosophila Dpr and DIP proteins belong to the immunoglobulin superfamily of cell
surface proteins (CSPs). Their hetero-and homophilic interactions have been implicated in a …

Mutations and knockout of aquaporin 0 (AQP0) result in dominant lens cataract. To date,
several functions have been proposed for AQP0; however, two functions, water permeability …

The lens has been considered to be an immune privileged site not susceptible to the
immune processes normally associated with tissue injury and wound repair. However, as …

Aquaporin 0 (AQP0), essential for lens clarity, is a tetrameric protein composed of four
identical monomers, each of which has its own water pore. The water permeability of AQP0 …

Purpose: The presence of a physical barrier to molecular diffusion through lenticular
extracellular space has been repeatedly detected. This extracellular diffusion barrier has …

Background Investigate the impact of natural N-or C-terminal post-translational truncations
of lens mature fiber cell Aquaporin 0 (AQP0) on water permeability (Pw) and cell-to-cell …

Purpose: Connexins and aquaporins play essential roles in maintaining lens homeostasis
and transparency and there is a close physical and functional relationship between these …