[HTML][HTML] The Arg233Lys AQP0 mutation disturbs aquaporin0-calmodulin interaction causing polymorphic congenital cataract

S Hu, B Wang, Y Qi, H Lin - PLoS One, 2012 - journals.plos.org
Calmodulin (CaM) directly interacts with the aquaporin 0 (AQP0) C-terminus in a calcium
dependent manner to regulate the water permeability of AQP0. We previously identified a …

[HTML][HTML] A novel MIP gene mutation analysis in a Chinese family affected with congenital progressive punctate cataract

X Ding, N Zhou, H Lin, J Chen, C Zhao, G Zhou… - PloS one, 2014 - journals.plos.org
Congenital cataracts are one of the leading causes of visual impairment and blindness in
children, and genetic factors play an important role in their development. This study aimed to …

The extracellular C-loop domain plays an important role in the cell adhesion function of aquaporin 0

Y Nakazawa, M Oka, M Funakoshi-Tago… - Current Eye …, 2017 - Taylor & Francis
ABSTRACT Purpose: Although aquaporin 0 (AQP0) is a member of the AQP family, it has
limited water permeability compared with other members. AQP0 may also have cell …

[HTML][HTML] Differences in a single extracellular residue underlie adhesive functions of two zebrafish Aqp0s

I Vorontsova, JE Hall, TF Schilling, N Nagai… - Cells, 2021 - mdpi.com
Aquaporin 0 (AQP0) is the most abundant lens membrane protein, and loss of function in
human and animal models leads to cataract formation. AQP0 has several functions in the …

[HTML][HTML] Aquaporin 1 (AQP1) expression in healthy dog tears

B Lamagna, P Ciaramella, F Lamagna, A Di Loria… - Animals, 2020 - mdpi.com
Simple Summary The characterisation of tear proteins is very important for scientists and
clinicians, as it enhances their understanding of ocular physiological phenomena that …

Functional Annotation Analytics of Rhodopseudomonas palustris Genomes

SS Simmons, RD Isokpehi, SD Brown… - … and Biology Insights, 2011 - journals.sagepub.com
Rhodopseudomonas palustris, a nonsulphur purple photosynthetic bacteria, has been
extensively investigated for its metabolic versatility including ability to produce hydrogen gas …

[HTML][HTML] Thermal Stress Induced Aggregation of Aquaporin 0 (AQP0) and Protection by α-Crystallin via Its Chaperone Function

S Swamy-Mruthinti, V Srinivas, JE Hansen, CM Rao - PLoS One, 2013 - journals.plos.org
Aquaporin 0 (AQP0) formerly known as membrane intrinsic protein (MIP), is expressed
exclusively in the lens during terminal differentiation of fiber cells. AQP0 plays an important …

[HTML][HTML] The common modification in αA-crystallin in the lens, N101D, is associated with increased opacity in a mouse model

R Gupta, CO Asomugha, OP Srivastava - Journal of Biological Chemistry, 2011 - ASBMB
To elucidate the morphological and cellular changes due to introduction of a charge during
development and the possible mechanism that underlies cataract development in humans …

A predominant form of C-terminally end-cleaved AQP0 functions as an open water channel and an adhesion protein in AQP0ΔC/ΔC mouse lens

SS Kumari, K Varadaraj - Biochemical and biophysical research …, 2019 - Elsevier
The purpose of this investigation was to find out whether C-terminally end-cleaved
aquaporin 0 (AQP0), that is present predominantly in the lens mature fiber cells of the WT …

Quantitative analysis of ascorbic acid permeability of aquaporin 0 in the lens

Y Nakazawa, M Oka, A Mitsuishi, M Bando… - Biochemical and …, 2011 - Elsevier
Aquaporin 0 (AQP0) is a lens-specific protein comprising more than 30% of lens membrane
protein content and is a member of the aquaporin family. Water permeates through AQP0 …