The common modification in αA-crystallin in the lens, N101D, is associated with increased opacity in a mouse model
R Gupta, CO Asomugha, OP Srivastava - Journal of Biological Chemistry, 2011 - ASBMB
To elucidate the morphological and cellular changes due to introduction of a charge during
development and the possible mechanism that underlies cataract development in humans …
development and the possible mechanism that underlies cataract development in humans …
Quantitative analysis of ascorbic acid permeability of aquaporin 0 in the lens
Y Nakazawa, M Oka, A Mitsuishi, M Bando… - Biochemical and …, 2011 - Elsevier
Aquaporin 0 (AQP0) is a lens-specific protein comprising more than 30% of lens membrane
protein content and is a member of the aquaporin family. Water permeates through AQP0 …
protein content and is a member of the aquaporin family. Water permeates through AQP0 …
A predominant form of C-terminally end-cleaved AQP0 functions as an open water channel and an adhesion protein in AQP0ΔC/ΔC mouse lens
SS Kumari, K Varadaraj - Biochemical and biophysical research …, 2019 - Elsevier
The purpose of this investigation was to find out whether C-terminally end-cleaved
aquaporin 0 (AQP0), that is present predominantly in the lens mature fiber cells of the WT …
aquaporin 0 (AQP0), that is present predominantly in the lens mature fiber cells of the WT …
Positively charged amino acid residues in the extracellular loops A and C of lens aquaporin 0 interact with the negative charges in the plasma membrane to facilitate …
S Kumari, G Taginik, S Varadaraj, K Varadaraj - Experimental eye research, 2019 - Elsevier
This investigation was undertaken to find out whether the positive charges in the
Extracellular Loops A (ELA) and C (ELC) of Aquaporin 0 (AQP0) are involved in lens fiber …
Extracellular Loops A (ELA) and C (ELC) of Aquaporin 0 (AQP0) are involved in lens fiber …
Expression of aquaporins in rat liver regeneration
KC Hung, PM Hsieh, CY Hsu, CW Lin… - Scandinavian journal …, 2012 - Taylor & Francis
Objective. The remarkable ability of liver to regenerate after insults has been harnessed by
surgeons when designing techniques for liver resection or transplantation. However, the …
surgeons when designing techniques for liver resection or transplantation. However, the …
Lens transcriptome profile during cataract development in Mip-null mice
TM Bennett, Y Zhou, A Shiels - Biochemical and biophysical research …, 2016 - Elsevier
Major intrinsic protein or aquaporin-0 (MIP/AQP0) functions as a water channel and a cell-
junction molecule in the vertebrate eye lens. Loss of MIP function in the lens leads to …
junction molecule in the vertebrate eye lens. Loss of MIP function in the lens leads to …
Aquaporins, anti-aquaporin-4 autoantibodies and neuromyelitis optica
C González, JM González-Buitrago, G Izquierdo - Clinica Chimica Acta, 2013 - Elsevier
The classification, distribution and functions of the different molecules of aquaporins (AQPs),
including aquaporins, aquaglyceroporins and superaquaporins are reviewed together with …
including aquaporins, aquaglyceroporins and superaquaporins are reviewed together with …
[PDF][PDF] Assessment of zebrafish lens nucleus localization and sutural integrity
I Vorontsova, JE Hall, TF Schilling - J. Vis. Exp, 2019 - researchgate.net
The zebrafish is uniquely suited to genetic manipulation and in vivo imaging, making it an
increasingly popular model for reverse genetic studies and for generation of transgenics for …
increasingly popular model for reverse genetic studies and for generation of transgenics for …
[HTML][HTML] Insight into the posttranslational modifications of tetrameric AQP0 isolated from bovine eye lens using native MS and surface-induced dissociation
SR Harvey, C O'Neale, KL Schey… - Analytical chemistry, 2022 - ncbi.nlm.nih.gov
Abstract Aquaporin-0 (AQP0) is a tetrameric membrane protein and is the most abundant
membrane protein in the eye lens. Interestingly, there is little to no cellular turnover once …
membrane protein in the eye lens. Interestingly, there is little to no cellular turnover once …
A novel missense mutation in the gene encoding major intrinsic protein (MIP) in a Giant panda with unilateral cataract formation
C Bai, Y You, X Liu, M Xia, W Wang, T Jia, T Pu, Y Lu… - BMC genomics, 2021 - Springer
Background Cataracts are defects of the lens that cause progressive visual impairment and
ultimately blindness in many vertebrate species. Most cataracts are age-related, but up to …
ultimately blindness in many vertebrate species. Most cataracts are age-related, but up to …