Mechanistic studies on the absorption enhancement of a self-nanoemulsifying drug delivery system loaded with norisoboldine-phospholipid complex
J Zhang, X Wen, Y Dai, Y Xia - International journal of …, 2019 - Taylor & Francis
Background Norisoboldine (NOR), the main isoquinoline alkaloid constituent in Radix
Linderae, was demonstrated to have an outstanding anti-arthritis activity. However, a poor …
Linderae, was demonstrated to have an outstanding anti-arthritis activity. However, a poor …
Quality by design approach for the development of self-emulsifying systems for oral delivery of febuxostat: pharmacokinetic and pharmacodynamic evaluation
N Rangaraj, S Shah, M AJ, SR Pailla, HS Cheruvu… - AAPS …, 2019 - Springer
The goal of the present investigation is to formulate febuxostat (FXT) self-nanoemulsifying
delivery systems (liquid SNEDDS, solid SNEDDS, and pellet) to ameliorate the solubility and …
delivery systems (liquid SNEDDS, solid SNEDDS, and pellet) to ameliorate the solubility and …
Quality by design approach for developing lipid-based nanoformulations of gliclazide to improve oral bioavailability and anti-diabetic activity
P Patel, SR Pailla, N Rangaraj, HS Cheruvu… - Aaps Pharmscitech, 2019 - Springer
The aim of the current investigation was to generate a self-nanoemulsifying drug delivery
system (SNEDDS) of gliclazide (GCZ) to address the poor solubility and bioavailability …
system (SNEDDS) of gliclazide (GCZ) to address the poor solubility and bioavailability …
[HTML][HTML] Improved dissolution and oral absorption by co-grinding active drug probucol and ternary stabilizers mixtures with planetary beads-milling method
F Li, L Li, S Wang, Y Yang, J Li, D Liu, S Zhang… - Asian Journal of …, 2019 - Elsevier
The objective of this work is to construct a nanosuspension drug delivery system of probucol,
a BCS II drug, in order to improve its dissolution and oral bioavailability. The wet milling …
a BCS II drug, in order to improve its dissolution and oral bioavailability. The wet milling …
[PDF][PDF] Enhancement of transdermal delivery of tamoxifen citrate using nanoemulsion vehicle
IB Pathan, CM Setty - Int J PharmTech Res, 2011 - academia.edu
The main objective of this study was to develop a potential of nanoemulsion formulation for
transdermal delivery of tamoxifene citrate for breast cancer. Of the oils tested, arachis oil was …
transdermal delivery of tamoxifene citrate for breast cancer. Of the oils tested, arachis oil was …
[HTML][HTML] Optimization of a cefuroxime axetil-loaded liquid self-nanoemulsifying drug delivery system: enhanced solubility, dissolution and caco-2 cell uptake
Cefuroxime axetil (CA) is an oral cephalosporin which hydrolyzes rapidly to the active parent
compound cefuroxime. CA is known to have incomplete oral bioavailability (30–50%) due to …
compound cefuroxime. CA is known to have incomplete oral bioavailability (30–50%) due to …
Preparation, optimization, and pharmacokinetic study of nanoliposomes loaded with triacylglycerol‐bound punicic acid for increased antihepatotoxic activity
M Adu‐Frimpong, CK Firempong… - Drug development …, 2019 - Wiley Online Library
Punicic acid of pomegranate oil (PAP) has gained heightened interest due to several health
benefits, such as anticarcinogenic, antidiabetic, and antiatherosclerotic properties. However …
benefits, such as anticarcinogenic, antidiabetic, and antiatherosclerotic properties. However …
[HTML][HTML] Synthesis of castor oil/poly (N-vinyl-2-pyrrolidone)/ammonium persulfate hybrids emulsion as textile softeners
Two castor oil/poly (N-vinyl-2-pyrrolidone)/ammonium persulfate (CAO/PVP/APS) hybrids
were synthesized via reaction of castor oil with PVP of molecular weights 40000 and …
were synthesized via reaction of castor oil with PVP of molecular weights 40000 and …
Self-microemulsifying drug-delivery system for improved oral bioavailability of probucol: preparation and evaluation
X Sha, J Wu, Y Chen, X Fang - International Journal of …, 2012 - Taylor & Francis
The objective of our investigation was to design a self-microemulsifying drug-delivery
system (SMEDDS) to improve the bioavailability of probucol. SMEDDS was composed of …
system (SMEDDS) to improve the bioavailability of probucol. SMEDDS was composed of …
A new function of Vitamin E-TPGS in the intestinal lymphatic transport of lipophilic drugs: enhancing the secretion of chylomicrons
Z Fan, J Wu, X Fang, X Sha - International journal of pharmaceutics, 2013 - Elsevier
The purpose of this study was to examine whether Vitamin E-TPGS had a function in
promoting the secretion of chylomicrons in enterocytes. Therefore, we simulated the human …
promoting the secretion of chylomicrons in enterocytes. Therefore, we simulated the human …