Diffuse Pleural Mesothelioma: Advances in Molecular Pathogenesis, Diagnosis, and Treatment

CA Febres-Aldana, R Fanaroff, M Offin… - Annual Review of …, 2024 - annualreviews.org
Diffuse pleural mesothelioma (DPM) is a highly aggressive malignant neoplasm arising from
the mesothelial cells lining the pleural surfaces. While DPM is a well-recognized disease …

Omics Overview of the SPARC Gene in Mesothelioma

L Wu, M de Perrot - Biomolecules, 2023 - mdpi.com
The SPARC gene plays multiple roles in extracellular matrix synthesis and cell shaping,
associated with tumor cell migration, invasion, and metastasis. The SPARC gene is also …

[HTML][HTML] Comprehensive analysis of the expression of cell adhesion molecules genes in hepatocellular carcinoma and their prognosis, and biological significance

J Wang, Y Hu, K Zhao, J Fan, J Zhu, Q Li… - Frontiers in Bioscience …, 2024 - imrpress.com
Background: Collagen-related cell adhesion molecules (CAMs) are a major component of
the extracellular matrix (ECM) and often accumulate in the liver during chronic liver disease …

[HTML][HTML] Characterization of KLHL14 anti-oncogenic action in malignant mesothelioma

A Canciello, RB Domínguez, B Barboni, A Giordano… - Heliyon, 2024 - cell.com
Malignant mesothelioma (MM) is a very aggressive neoplasia with a short life expectancy
and limited therapeutic options. Thus, the identification of novel molecular targets is a matter …

Identification of the ferroptosis-related prognostic gene signature in mesothelioma

Z Wang, J Huang, L Fu, S Liu, J Huang, J Han, X Zhao - Gene, 2024 - Elsevier
Mesothelioma, an uncommon yet highly aggressive malignant neoplasm, presents
challenges in the effectiveness of current therapeutic approaches. Ferroptosis, a non …

[HTML][HTML] Diagnostic, prognostic, and therapeutic implications of genetic profiling in pleural mesothelioma

A Sadek, A De Rienzo, R Bueno - Journal of Cancer Metastasis …, 2023 - oaepublish.com
Pleural mesothelioma (PM) is an aggressive malignancy of the pleural lining that typically
arises secondary to asbestos exposure. With the advent of next-generation sequencing …