Kisspeptin (KP) and neurokinin B (NKB) are neuropeptides that govern the reproductive
endocrine axis through regulating hypothalamic gonadotropin-releasing hormone (GnRH) …

Chronic stress, even stress of a moderate intensity related to daily life, is widely
acknowledged to be a predisposing or precipitating factor in neuropsychiatric diseases …

Abstract Knowledge gaps that limit the development of therapies for polycystic ovary
syndrome (PCOS) concern various environmental factors that impact clinical characteristics …

BACKGROUND Hypoactive sexual desire disorder (HSDD) is characterized by a persistent
deficiency of sexual fantasies and desire for sexual activity, causing marked distress and …

Importance The human physiological sexual response is crucial for reward, satisfaction, and
reproduction. Disruption of the associated neurophysiological pathways predisposes to low …

Galanin is a biologically active neuropeptide, and functions through three distinct G protein–
coupled receptors (GPCRs), namely GALR1, GALR2, and GALR3. GALR signaling plays …

Background There is limited comprehensive evidence on the potential association between
early menarche and subsequent health outcomes. Aim To evaluate the existing evidence for …

Background and aims Galanin is a naturally occurring peptide that plays a critical role in
regulating inflammation and energy metabolism, with expression in the liver. The exact …

According to World Health Organization estimates, 5% of the adult population worldwide
suffers from depression. In addition to the affective, psychomotor and cognitive symptoms …

Spexin is the most recently discovered member of the galanin/kisspeptin/spexin family of
peptides. This 14-amino acid peptide is highly conserved and is implicated in homeostatic …