Amyotrophic lateral sclerosis (ALS) is a rapidly debilitating fatal neurodegenerative disorder,
causing muscle atrophy and weakness, which leads to paralysis and eventual death. ALS …

Over the years, researchers have leveraged a host of different in vivo models in order to
dissect amyotrophic lateral sclerosis (ALS), a neurodegenerative/neuroinflammatory …

Motor neurons and their axons reaching the skeletal muscle have long been considered as
the best characterized targets of the degenerative process observed in amyotrophic lateral …

Amyotrophic Lateral Sclerosis (ALS) is a motor neurodegenerative disorder whose cellular
hallmarks are the progressive death of motor neurons (MNs) located in the anterior horn of …

Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease in which the
motor neuron circuitry displays progressive degeneration, affecting mostly the motor …

Nerve injury of the central nervous system and the peripheral nervous system still poses a
major challenge in modern clinics. Understanding the roles of neurotrophic factors and their …

Amyotrophic lateral sclerosis is a fatal adult-onset neurodegenerative disease characterized
by progressive muscular weakness and atrophy. The primary feature of amyotrophic lateral …

Amyotrophic lateral sclerosis (ALS) is a cruel neurodegenerative disease resulting in
eventual paralysis, respiratory dysfunction, and death, typically within 2-4 years from …

The promise of pluripotent stem cell (PSC)-based neuronal models and therapeutic
solutions is dependent upon how well they replicate in vivo phenotypes and function …

An amyotrophic lateral sclerosis is a group of progressive neurodegenerative disorders of
motor neurons that leads to weakness, muscle atrophy, progressive paralysis, and …