In situ imaging of metals in cells and tissues

R McRae, P Bagchi, S Sumalekshmy… - Chemical …, 2009 - ACS Publications
Approximately one third of the human proteome contains metal cations, either in the form of
cofactors with catalytic functions or as structural support elements. 1, 2 To guarantee a …

Organ damage by toxic metals is critically determined by the bloodstream

S Sarpong-Kumankomah, MA Gibson… - Coordination Chemistry …, 2018 - Elsevier
Past poisoning epidemics have revealed that the chronic exposure to exceedingly small
daily doses of toxic metal and metalloid species can–over time–severely affect human …

Impact of Early Arsenic Exposure on the Mineral Content and Oxidative Status of the Liver and Kidney of Pubescent and Adult Rats

F Couto-Santos, LO Guimarães-Ervilha… - … Trace Element Research, 2024 - Springer
This study evaluated the effect of prepubertal arsenic exposure in the liver and kidney of
pubescent rats and their reversibility 30 days after arsenic withdrawal. Male pups of Wistar …

Combined effects of arsenic exposure and diabetes on male reproductive functions

ACF Souza, DSS Bastos, MN Sertorio, FC Santos… - …, 2019 - Wiley Online Library
Background It is known that exposure to either arsenic or hyperglycemia can induce male
reproductive damages. However, their combined effects on male reproductive organs are …

Effects of arsenic exposure on trace element levels in the hippocampus and cortex of rats and their gender differences

X Yan, J Zhang, J Li, X Zhang, Y Wang, X Chen… - Journal of Trace …, 2023 - Elsevier
Abstract Background Exposure to arsenic (As) is a major public health challenge worldwide.
Chronic exposure to As can cause various human health effects, including skin diseases …

Translational toxicology of metal (loid) species: Linking their bioinorganic chemistry in the bloodstream to organ damage onset

M Doroudian, N Pourzadi, A Gautam, J Gailer - Biometals, 2024 - Springer
The quantification of arsenic, mercury, cadmium and lead in the human bloodstream is
routinely used today to assess exposure to these toxic metal (loid) s, but the interpretation of …

Hydroalcoholic seed extract of Coriandrum sativum (Coriander) alleviates lead-induced oxidative stress in different regions of rat brain

MK Velaga, PR Yallapragada, D Williams… - Biological trace element …, 2014 - Springer
Lead exposure is known to cause apoptotic neurodegeneration and neurobehavioral
abnormalities in developing and adult brain by impairing cognition and memory …

Effects of arsenic compounds on microminerals content and antioxidant enzyme activities in rat liver

ACF Souza, SC Marchesi, GD de Almeida Lima… - Biological trace element …, 2018 - Springer
Interactions of arsenic with essential trace elements may result in disturbances on body
homeostasis. In the present study, we aimed to investigate the effects of different arsenic …

Effect of selenomethionine supplementation in food on the excretion and toxicity of arsenic exposure in female mice

M Rodríguez-Sosa, EA García-Montalvo… - Biological trace element …, 2013 - Springer
Selenium (Se) is an essential component of several major metabolic pathways and controls
immune function. Arsenic (As) is a human carcinogen with immunotoxic and genotoxic …

Probing the bioinorganic chemistry of toxic metals in the mammalian bloodstream to advance human health

J Gailer - Journal of inorganic biochemistry, 2012 - Elsevier
The etiology of numerous grievous human diseases, including Alzheimer's and Parkinson's
Disease is not well understood. Conversely, the concentration toxic metals and metalloids …