Schizophrenia is a common multigenic and debilitating neurological disorder characterized
by chronic psychotic symptoms and psychosocial impairment. Complex interactions of …

The ability to identify and characterize not only the protein-protein interactions but also their
internal modular organization through network analysis is fundamental for understanding …

Schizophrenia (Scz) is a brain disorder that has a typical onset in early adulthood but
otherwise maintains unknown disease origins. Unfortunately, little progress has been made …

Background The increased mutational burden for rare structural genomic variants in
schizophrenia and other neurodevelopmental disorders has so far not yielded therapies …

Our recent study has demonstrated that increased connectivity in the cerebello-thalamo-
cortical (CTC) circuitry is a state-independent neural trait that can potentially predict the …

It is widely accepted, given the complex nature of schizophrenia (SCZ) gene networks, that a
few or a small number of genes are unlikely to represent the underlying functional pathways …

Synapse-to-nucleus signaling is critical for converting signals received at synapses into
transcriptional programs essential for cognition, memory, and emotion. This neuronal …

Prenatal exposure to polyriboinosinic–polyribocytidylic acid (poly I: C) results in psychotic-
like behavior in mature rat offspring as well as enduring modifications of glutamatergic …

Cognitive impairments characterize individuals with schizophrenia, and are correlated to the
patients' functional outcome. The transcription factor Cyclic AMP-responsive element …

Neurodevelopmental disorders, including autism spectrum disorder, have complex
polygenic etiologies. Single-gene mutations in patients can help define genetic factors and …