[HTML][HTML] Treatment options for PNET liver metastases: a systematic review

G Nigri, N Petrucciani, T Debs, LM Mangogna… - World journal of surgical …, 2018 - Springer
Abstract Background Pancreatic neuroendocrine tumors (PNETs) are rare pancreatic
neoplasms. About 40–80% of patients with PNET are metastatic at presentation, usually …

[HTML][HTML] mTOR pathway in gastroenteropancreatic neuroendocrine tumor (GEP-NETs)

S Zanini, S Renzi, F Giovinazzo… - Frontiers in …, 2020 - frontiersin.org
Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) originate from
neuroendocrine cells in the gastrointestinal tract. They are heterogeneous, and though …

The spectrum of neuroendocrine tumors: histologic classification, unique features and areas of overlap

DS Klimstra, H Beltran, R Lilenbaum… - American Society of …, 2015 - ascopubs.org
Neuroendocrine neoplasms are diverse in terms of sites of origin, functional status, and
degrees of aggressiveness. This review will introduce some of the common features of …

[HTML][HTML] A systems biology approach to define mechanisms, phenotypes, and drivers in PanNETs with a personalized perspective

SD Werle, N Ikonomi, L Lausser… - npj Systems Biology …, 2023 - nature.com
Pancreatic neuroendocrine tumors (PanNETs) are a rare tumor entity with largely
unpredictable progression and increasing incidence in developed countries. Molecular …

[HTML][HTML] Risk and protective factors for the occurrence of sporadic pancreatic endocrine neoplasms

R Valente, AJ Hayes, SP Haugvik… - Endocrine-related …, 2017 - erc.bioscientifica.com
Pancreatic neuroendocrine neoplasms (PNENs) represent 10% of all pancreatic tumors by
prevalence. Their incidence has reportedly increased over recent decades in parallel with …

Predictive markers of response to everolimus and sunitinib in neuroendocrine tumors

D Martins, F Spada, I Lambrescu, M Rubino, C Cella… - Targeted …, 2017 - Springer
Neuroendocrine tumors (NETs) represent a large and heterogeneous group of malignancies
with various biological and clinical characteristics, depending on the site of origin and the …

MYC upregulation confers resistance to everolimus and establishes vulnerability to cyclin-dependent kinase inhibitors in pancreatic neuroendocrine neoplasm cells

F Terracciano, A Capone, A Montori, M Rinzivillo… - …, 2021 - karger.com
Introduction: Dysregulation of the mechanistic target of rapamycin complex 1 (mTORC1)-
dependent pathways in pancreatic neuroendocrine neoplasms (PanNENs) underlies the …

An update on the management of pancreatic neuroendocrine tumors

L Gao, NS Natov, KP Daly, F Masud… - Anti-cancer …, 2018 - journals.lww.com
Pancreatic neuroendocrine tumors (PNETs) are a rare and heterogeneous group of
neoplasia and differ in their clinical presentation, behavior, and prognosis based on both …

Digestive neuroendocrine neoplasms: A 2016 overview

E Merola, M Rinzivillo, N Cicchese, G Capurso… - Digestive and Liver …, 2016 - Elsevier
Digestive neuroendocrine neoplasms (DNENs) have an incidence of 2.39 per 100,000
inhabitants per year, and a prevalence of 35 cases per 100,000; the gap between these …

CT radiogenomic characterization of the alternative lengthening of telomeres phenotype in pancreatic neuroendocrine tumors

JM McGovern, AD Singhi, AA Borhani… - American Journal of …, 2018 - Am Roentgen Ray Soc
OBJECTIVE. The objective of this study was to identify imaging characteristics in patients
with known pancreatic neuroendocrine tumors (PanNETs) that predict the alternative …