Complement System and C4d expression in cases of Membranous nephropathy

FB Custódio, CA Silva, FR Helmo… - Jornal Brasileiro de …, 2017 - SciELO Brasil
Introduction: Membranous nephropathy (MN) is one of the major causes of nephrotic
syndrome. The complement system plays a key role in the pathophysiology of MN …

Membranous nephropathy in the kidney allograft

EJ Filippone, JL Farber - Clinical transplantation, 2016 - Wiley Online Library
Membranous nephropathy (MN) may occur in a kidney transplant as recurrence of the
original disease (rMN) or as a de novo MN (dnMN). rMN often occurs early, within the first …

Bioinformatic investigation for candidate genes and molecular mechanism in the pathogenesis of membranous nephropathy

P Li, X Zhong, L Zhang, Y Yu, J Niu - Nephrology, 2021 - Wiley Online Library
Aim We aimed to explore the detailed molecular mechanism of immune‐associated genes
in membranous nephropathy (MN). Methods A microarray data set (GSE133288) was …

PLA2R antibodies and PLA2R glomerular deposits in psoriasis patients with membranous nephropathy

YC Ge, B Jin, CH Zeng, MC Zhang, DC Chen, R Yin… - BMC nephrology, 2016 - Springer
Background The association between psoriasis and membranous nephropathy (MN)
remains largely unclear. We examined the prevalence of serum PLA2R antibody and …

Is There a Place for Apheresis in the Management of Idiopathic Membranous Nephropathy? A Report of Three Cases and Literature Review

H Naciri Bennani, AT Banza, D Giovannini… - Journal of Personalized …, 2024 - mdpi.com
Membranous nephropathy constitutes approximately 20% of adult nephrotic syndrome
cases. In approximately 80% of cases, membranous nephropathy is primary, mediated by …

Is systemic lupus erythematosus linked to Immunoglobulin G4 Autoantibodies?

S Wei, Q Xiong, H Yao, Q He, P Yu - Human Immunology, 2024 - Elsevier
Systemic lupus erythematosus (SLE) is a systemic autoimmune disorder characterized by a
hyperactive immune system with multiple abnormalities in B-cell proliferation, antibody …

[HTML][HTML] Complement cascade and kidney transplantation: The rediscovery of an ancient enemy

A Mella, M Messina, A Lavacca… - World journal of …, 2014 - ncbi.nlm.nih.gov
The identification of complement activity in serum and immunohistochemical samples
represents a core element of nephropathology. On the basis of this observation, different …

Clusterin deficiency predisposes C57BL/6j mice to cationic bovine serum albumin-induced glomerular inflammation

P Sun, S Feng, Q Guan, H Adomat… - Journal of …, 2020 - Taylor & Francis
Background Membranous nephropathy (MN) is a specific entity of glomerulonephritis, and
its glomerular inflammation is characterized by the deposition of immune complexes in the …

A comprehensive narrative review of diagnostic biomarkers in human primary membranous nephropathy

S Kalantari, M Nafar - Biomarkers in Medicine, 2017 - Taylor & Francis
Membranous nephropathy (MN) is relatively major cause of nephrotic syndrome in adults
which is recognized as an organ-specific autoimmune disease. The etiology of most cases is …

Kidney diseases

E Daina, M Cortinovis, G Remuzzi - Immunological Reviews, 2023 - Wiley Online Library
Dysregulation and accelerated activation of the alternative pathway (AP) of complement is
known to cause or accentuate several pathologic conditions in which kidney injury leads to …