Trabectedin and Lurbinectedin Modulate the Interplay between Cells in the Tumour Microenvironment—Progresses in Their Use in Combined Cancer Therapy

A Povo-Retana, R Landauro-Vera, C Alvarez-Lucena… - Molecules, 2024 - mdpi.com
Trabectedin (TRB) and Lurbinectedin (LUR) are alkaloid compounds originally isolated from
Ecteinascidia turbinata with proven antitumoral activity. Both molecules are structural …

A Comprehensive Review of Genistein's Effects in Preclinical Models of Cervical Cancer

M Nadile, A Kornel, NSK Sze, E Tsiani - Cancers, 2023 - mdpi.com
Simple Summary Cervical cancer is the fourth most commonly diagnosed cancer among
women worldwide. While treatments exist to stop growth of cervical cancer in humans, they …

Research progress on the application of organoids in gynecological tumors

Y Shen, Y Wang, S Wang, C Li, FJ Han - Frontiers in Pharmacology, 2024 - frontiersin.org
Organoids are in vitro 3D models that maintain their own tissue structure and function. They
largely overcome the limitations of traditional tumor models and have become a powerful …

[HTML][HTML] Effects of chronic stress on cancer development and the therapeutic prospects of adrenergic signaling regulation

H Zhang, Y Yang, Y Cao, J Guan - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Long-term chronic stress is an important factor in the poor prognosis of cancer patients.
Chronic stress reduces the tissue infiltration of immune cells in the tumor microenvironment …

β-adrenergic modulation of IL-6/gp130 and SOCS-1 in multiple myeloma: therapeutic strategy for stress induced-inflammatory response

R Naiebi, S Abroun, A Atashi, L Shafiee… - memo-Magazine of …, 2024 - Springer
Summary Purpose Multiple Myeloma (MM) is considered an incurable, biologically
heterogeneous disease of the plasma cells. The clinical data on the association between …