In multicellular organisms, angiogenesis, the formation of new blood vessels from pre-
existing ones, is an essential process for growth and development. Different mechanisms …

Abstract Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) is presenting as a systemic disease associated with …

Coronavirus disease 2019 (COVID-19) is associated with a prothrombotic phenotype
characterised by coagulopathy and endothelial dysfunction [1–4]. Following some cases of …

COVID-19 is a primary respiratory illness that is frequently complicated by systemic
involvement of the vasculature. Vascular involvement leads to an array of complications …

Abstract The coronavirus disease 2019 (COVID-19) is a highly transmissible disease
caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that poses a …

Background SARS-CoV-2 targets endothelial cells through the angiotensin-converting
enzyme 2 receptor. The resulting endothelial injury induces widespread thrombosis and …

von Willebrand factor (VWF) is a large adhesive multimeric protein involved in hemostasis.
The larger the size (or number of VWF multimers), the greater the functionality of the protein …

Abstract Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory
syndrome coronavirus-2 (SARS-CoV-2), has become a global epidemic and poses a major …

Background SARS-CoV-2 infection is associated with thrombotic and microvascular
complications. The cause of coagulopathy in the disease is incompletely understood …

The global propagation of SARS-CoV-2 leads to an unprecedented public health
emergency. Despite that the lungs are the primary organ targeted by COVID-19, systemic …