Major Depressive Disorder (MDD) is a leading cause of disability worldwide, creating a high
medical and socioeconomic burden. There is a growing interest in the biological …

The innate immune system is dysregulated in depression; however, less is known about the
longitudinal associations of depression and inflammatory biomarkers. We investigated the …

Several lines of evidence suggest that stress induces the neurovascular dysfunction
associated with increased blood–brain barrier (BBB) permeability, which could be an …

A plethora of research has implicated hundreds of putative biomarkers for depression, but
has not yet fully elucidated their roles in depressive illness or established what is abnormal …

Major depressive disorder (MDD) is a heterogeneous disease affecting one out of five
individuals and is the leading cause of disability worldwide. Presently, MDD is considered a …

The most common mood disorders are major depressive disorders and bipolar disorders
(BD). The pathophysiology of BD is complex, multifactorial, and not fully understood …

The COVID-19 pandemic is spreading around the world and 187 million people have
already been affected. One of its after-effects is post-COVID depression, which, according to …

Major depressive disorder (MDD) is a debilitating psychiatric illness. However, there is
currently no objective laboratory-based diagnostic tests for this disorder. Although …

Major depressive disorder (MDD) is a very common disease that affects more than 350
million people worldwide, representing an enormous socioeconomic burden. From a clinical …

Background Mood disorders, including major depressive disorder, are among the main
causes of disability and early mortality and constitute an important public health problem …