Candida albicans is among the most prevalent fungal species of the human microbiota and
asymptomatically colonizes healthy individuals. However, it is also an opportunistic …

Unlike superficial fungal infections of the skin and nails, which are the most common fungal
diseases in humans, invasive fungal infections carry high morbidity and mortality …

Emerging pathogen Candida auris causes nosocomial outbreaks of life-threatening invasive
candidiasis. It is unclear how this species colonizes skin and spreads in health care …

Candida albicans is a normal member of the human microbiota that asymptomatically
colonizes healthy individuals, however it is also an opportunistic pathogen that can cause …

Systemic infections of Candida species pose a significant threat to public health. Toxicity
associated with current therapies and emergence of resistant strains present major …

We examine how a complex transcription network composed of seven 'master'regulators
and hundreds of target genes evolved over a span of approximately 70 million years. The …

Biofilms formed by the fungal pathogen Candida albicans are resistant to many of the
antifungal agents commonly used in the clinic. Previous reports suggest that protease …

Candida auris readily colonizes skin and efficiently spreads among patients in healthcare
settings worldwide. Given the capacity of this drug-resistant fungal pathogen to cause …

The unfolded protein response (UPR), crucial for the maintenance of endoplasmic reticulum
(ER) homeostasis, is tied to the regulation of multiple cellular processes in pathogenic fungi …

Biofilm formation by Candida albicans is a key aspect of its pathobiology and is regulated by
an integrated network of transcription factors (Bcr1, Brg1, Efg1, Ndt80, Rob1, and Tec1). To …