Multifunctional nanotheranostics for near infrared optical imaging-guided treatment of brain tumors

L Zhang, Y Liu, H Huang, H Xie, B Zhang, W Xia… - Advanced drug delivery …, 2022 - Elsevier
Malignant brain tumors, a heterogeneous group of primary and metastatic neoplasms in the
central nervous system (CNS), are notorious for their highly invasive and devastating …

Oxidative stress-induced apoptosis and autophagy: Balancing the contrary forces in spermatogenesis

P Sharma, N Kaushal, LR Saleth, S Ghavami… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Spermatogenesis is a complex process in the testis and is a cornerstone of male infertility.
The abundance of unsaturated fatty acid and high cell division rate make male germs cells …

Treatment with mesenchymal stem cell‐derived nanovesicle‐containing gelatin methacryloyl hydrogels alleviates osteoarthritis by modulating chondrogenesis and …

L Pang, H Jin, Z Lu, F Xie, H Shen, X Li… - Advanced …, 2023 - Wiley Online Library
Osteoarthritis is a degenerative disorder that can severely affect joints, and new treatment
strategies are urgently needed. Administration of mesenchymal stem cell (MSC)‐derived …

[HTML][HTML] A mesenchymal stem cell-derived nanovesicle-biopotentiated bovine serum albumin-bridged gelatin hydrogel for enhanced diabetic wound therapy

Y Wu, M Su, S Zhang, L Xiao, Y Xiao, M Zhang, Y Bei… - Materials & Design, 2023 - Elsevier
The application of gelatin hydrogels is hampered by their poor mechanical properties, which
are unfavorable for debridement and diabetic wound healing. Herein, bovine serum albumin …

Translating extracellular vesicle packaging into therapeutic applications

DC Ozkocak, TK Phan, IKH Poon - Frontiers in immunology, 2022 - frontiersin.org
Extracellular vesicles (EVs) are membrane-bound particles released by cells in various
(patho) physiological conditions. EVs can transfer effector molecules and elicit potent …

Translational and clinical applications of dental stem cell-derived exosomes

Z Mai, H Chen, Y Ye, Z Hu, W Sun, L Cui… - Frontiers in genetics, 2021 - frontiersin.org
Mesenchymal stem cells (MSCs) are promising seed cells in tissue repair and regeneration
due to their featured properties of self-renewal and multipotency. However, a growing body …

Extracellular vesicles in triple–negative breast cancer: Immune regulation, biomarkers, and immunotherapeutic potential

K Das, S Paul, A Ghosh, S Gupta, T Mukherjee… - Cancers, 2023 - mdpi.com
Simple Summary Triple–negative breast cancer (TNBC), an aggressive phenotype, is
commonly attributed to the loss of estrogen receptor, progesterone receptor, and human …

Characterization and therapeutic use of extracellular vesicles derived from platelets

T Spakova, J Janockova, J Rosocha - International Journal of Molecular …, 2021 - mdpi.com
Autologous blood products, such as platelet-rich plasma (PRP), are gaining increasing
interest in different fields of regenerative medicine. Although growth factors, the main …

Multipotent mesenchymal stem cell-based therapies for spinal cord injury: current progress and future prospects

CW Zeng - Biology, 2023 - mdpi.com
Simple Summary Mesenchymal stem cells (MSCs) are a promising option for developing
new treatments for spinal cord injury (SCI). They can help repair damaged tissue, making …

[HTML][HTML] Engineered mesenchymal stem cell-derived small extracellular vesicles for diabetic retinopathy therapy through HIF-1α/EZH2/PGC-1α pathway

F Sun, Y Sun, X Wang, J Zhu, S Chen, Y Yu, M Zhu… - Bioactive Materials, 2024 - Elsevier
Diabetic retinopathy (DR) is a leading cause of blindness worldwide with limited treatment
options. Mesenchymal stem cell-derived small extracellular vesicles (MSC-sEVs) hold …