Management of coronary artery disease in older adults: recent advances and gaps in evidence

S Cacciatore, L Spadafora, M Bernardi, M Galli… - Journal of clinical …, 2023 - mdpi.com
Coronary artery disease (CAD) is highly prevalent in older adults, yet its management
remains challenging. Treatment choices are made complex by the frailty burden of older …

Promising remedies for cardiovascular disease: Natural polyphenol ellagic acid and its metabolite urolithins

J Li, R Liao, S Zhang, H Weng, Y Liu, T Tao, F Yu, G Li… - Phytomedicine, 2023 - Elsevier
Background Cardiovascular disease (CVD) is a significant worldwide factor contributing to
human fatality and morbidity. With the increase of incidence rates, it is of concern that there …

Statins use and COVID-19 outcomes in hospitalized patients

SK Ayeh, EJ Abbey, BAA Khalifa, RD Nudotor… - PLoS …, 2021 - journals.plos.org
Background There is an urgent need for novel therapeutic strategies for reversing COVID-19-
related lung inflammation. Recent evidence has demonstrated that the cholesterol-lowering …

Association between age and low-density lipoprotein cholesterol response to statins: a Danish nationwide cohort study

G Corn, M Melbye, MA Hlatky, J Wohlfahrt… - Annals of Internal …, 2023 - acpjournals.org
Background: There is large patient-to-patient variability in the low-density lipoprotein
cholesterol (LDL-C) response to statin treatment. The reduction in LDL-C may depend on …

Should we interfere with the interleukin-6 receptor during COVID-19: what do we know so far?

A Plocque, C Mitri, C Lefèvre, O Tabary, L Touqui… - Drugs, 2023 - Springer
Severe manifestations of COVID-19 consist of acute respiratory distress syndrome due to an
initially local reaction leading to a systemic inflammatory response that results in hypoxia …

[HTML][HTML] The integrated study on the chemical profiling to explore the constituents and mechanism of traditional Chinese medicine preparation Huatuo Jiuxin pills …

Y Zhu, Y Zhu, S Tao, W Liang, J Zhang… - Frontiers in Molecular …, 2022 - frontiersin.org
Huatuo Jiuxin Pills (HJP), a traditional Chinese medicine (TCM) preparation, has been
widely used to treat Cardiovascular Diseases (CVDs) for more than 20 years. However …

Aspirin, statins, and primary prevention: opportunities for shared decision making in the face of uncertainty

A Jhaveri, RA Sibley, ES Spatz, J Dodson - Current Cardiology Reports, 2021 - Springer
Abstract Purpose of Review The utility of aspirin and statins for primary prevention of
atherosclerotic cardiovascular disease remains ambiguous in older adults. Current …

Use of lipid-lowering drugs and associated outcomes according to health state profiles in hospitalized older patients

C Franchi, G Lancellotti, M Bertolotti… - … Interventions in Aging, 2021 - Taylor & Francis
Objective To assess how lipid-lowering drugs (LLDs) are administered in the hospitalized
patients aged 65 and older and their association with clinical outcomes according to their …

Potential role of statins in treatment of acute sarcopenia

A De Spiegeleer, H Kahya, L Crombez, A Descamps… - Medical …, 2023 - Elsevier
Accelerated muscle aging, known as sarcopenia, is a geriatric condition that poses
significant health risks both for individuals and society. Hospitalization can trigger a sudden …

Authors' Reply to Chia Siang Kow et al.: Comment on:'Should We Interfere with the Interleukin-6 Receptor During COVID-19: What Do We Know So Far?'

A Plocque, F Philippart - Drugs, 2023 - Springer
We do thank Dr. Chia Siang Kow and his colleagues for their very interesting comment
about the unknown and delayed potential complications associated with the inhibition of …