Advancing the global public health agenda for NAFLD: a consensus statement

JV Lazarus, HE Mark, QM Anstee, JP Arab… - Nature Reviews …, 2022 - nature.com
Non-alcoholic fatty liver disease (NAFLD) is a potentially serious liver disease that affects
approximately one-quarter of the global adult population, causing a substantial burden of ill …

Macrophage functional diversity in NAFLD—more than inflammation

E Barreby, P Chen, M Aouadi - Nature Reviews Endocrinology, 2022 - nature.com
Macrophages have diverse phenotypes and functions due to differences in their origin,
location and pathophysiological context. Although their main role in the liver has been …

[HTML][HTML] The global NAFLD policy review and preparedness index: Are countries ready to address this silent public health challenge?

JV Lazarus, HE Mark, M Villota-Rivas, A Palayew… - Journal of …, 2022 - Elsevier
Background & Aims Non-alcoholic fatty liver disease (NAFLD) is a highly prevalent, yet
largely underappreciated liver condition which is closely associated with obesity and …

[HTML][HTML] Non-alcoholic fatty liver disease: A patient guideline

SM Francque, G Marchesini, A Kautz, M Walmsley… - JHEP reports, 2021 - Elsevier
This patient guideline is intended for all patients at risk of or living with non-alcoholic fatty
liver disease (NAFLD). NAFLD is the most frequent chronic liver disease worldwide and …

A researcher's guide to preclinical mouse NASH models

S Gallage, JEB Avila, P Ramadori, E Focaccia… - Nature …, 2022 - nature.com
Non-alcoholic fatty liver disease (NAFLD) and its inflammatory form, non-alcoholic
steatohepatitis (NASH), have quickly risen to become the most prevalent chronic liver …

Nonalcoholic fatty liver disease as a metabolic disease in humans: A literature review

B Cariou, CD Byrne, R Loomba… - Diabetes, Obesity and …, 2021 - Wiley Online Library
Aims To conduct a systematic literature review to identify recent epidemiological, biomarker,
genetic and clinical evidence that expands our understanding of nonalcoholic fatty liver …

Caucasian lean subjects with non-alcoholic fatty liver disease share long-term prognosis of non-lean: time for reappraisal of BMI-driven approach?

R Younes, O Govaere, S Petta, L Miele, D Tiniakos… - Gut, 2022 - gut.bmj.com
Objective The full phenotypic expression of non-alcoholic fatty liver disease (NAFLD) in lean
subjects is incompletely characterised. We aimed to investigate prevalence, characteristics …

Defining comprehensive models of care for NAFLD

JV Lazarus, QM Anstee, H Hagström, K Cusi… - Nature reviews …, 2021 - nature.com
Non-alcoholic fatty liver disease (NAFLD) is now the leading cause of chronic liver disease
globally. Despite the increased demand placed on health-care systems, little attention has …

[HTML][HTML] Metabolic drivers of non-alcoholic fatty liver disease

KK Bence, MJ Birnbaum - Molecular metabolism, 2021 - Elsevier
Background The incidence of non-alcoholic fatty liver disease (NAFLD) is rapidly increasing
worldwide parallel to the global obesity epidemic. NAFLD encompasses a range of liver …

Comparative burden of metabolic dysfunction in lean NAFLD vs non-lean NAFLD-a systematic review and meta-analysis

A Tang, CH Ng, PH Phang, KE Chan, YH Chin… - Clinical …, 2023 - Elsevier
Background & Aims Nonalcoholic fatty liver disease (NAFLD) is traditionally associated with
obesity. However, there is a subtype of NAFLD, namely NAFLD in lean, that occurs without …