Quantitative phase microscopy for evaluation of intestinal inflammation and wound healing utilizing label-free biophysical markers

D Bettenworth, A Bokemeyer, C Poremba, NS Ding… - 2018 - digitum.um.es
Inflammatory bowel diseases (IBD) are inflammatory disorders of the gastrointestinal tract
characterized by a chronic relapsing disease course. As uncontrolled intestinal inflammation …

Label-free digital holographic microscopy for in vitro cytotoxic effect quantification of organic nanoparticles

KM Eder, A Marzi, Á Barroso, S Ketelhut, B Kemper… - Cells, 2022 - mdpi.com
Cytotoxicity quantification of nanoparticles is commonly performed by biochemical assays to
evaluate their biocompatibility and safety. We explored quantitative phase imaging (QPI) …

Simple and fast spectral domain algorithm for quantitative phase imaging of living cells with digital holographic microscopy

J Min, B Yao, S Ketelhut, C Engwer, B Greve… - Optics Letters, 2017 - opg.optica.org
We present a simple and fast phase aberration compensation method in digital holographic
microscopy (DHM) for quantitative phase imaging of living cells. By analyzing the frequency …

Interlaboratory evaluation of a digital holographic microscopy–based assay for label-free in vitro cytotoxicity testing of polymeric nanocarriers

A Marzi, KM Eder, Á Barroso, AM Wågbø… - Drug delivery and …, 2022 - Springer
State-of-the-art in vitro test systems for nanomaterial toxicity assessment are based on dyes
and several staining steps which can be affected by nanomaterial interference. Digital …

Quantitative phase imaging using digital holographic microscopy reliably assesses morphology and reflects elastic properties of fibrotic intestinal tissue

A Bokemeyer, PR Tepasse, L Quill, P Lenz, E Rijcken… - Scientific reports, 2019 - nature.com
Intestinal strictures are a frequent complication in patients with Crohn's Disease (CD) and
the presence of fibrosis within strictures impacts the therapeutic treatment approach. Here …

Quantitative phase imaging using digital holographic microscopy to assess the degree of intestinal inflammation in patients with ulcerative colitis

A Bokemeyer, J Buskermolen, S Ketelhut… - Journal of Clinical …, 2023 - mdpi.com
Ulcerative colitis (UC) is characterized by chronic inflammation of the colorectum.
Histological remission has emerged as a potential future treatment goal; however, the …

Digital holographic microscopy for label-free detection of leukocyte alternations associated with perioperative inflammation after cardiac surgery

DR Steike, M Hessler, E Korsching, F Lehmann… - Cells, 2022 - mdpi.com
In a prospective observational pilot study on patients undergoing elective cardiac surgery
with cardiopulmonary bypass, we evaluated label-free quantitative phase imaging (QPI) with …

Dynamic phase measurement of a transparent object by parallel phase-shifting digital holography with dual polarization imaging cameras

P Xia, S Ri, T Inoue, Y Awatsuji, O Matoba - Optics and Lasers in …, 2021 - Elsevier
Measurement of surface shape and refractive index for moving transparent objects is critical
in various fields. A parallel phase-shifting digital holography system that can record and …

Exploiting the potential of commercial digital holographic microscopy by combining it with 3D matrix cell culture assays

M Hellesvik, H Øye, H Aksnes - Scientific Reports, 2020 - nature.com
Abstract 3D cell culture assays are becoming increasingly popular due to their higher
resemblance to tissue environment. These provide an increased complexity compared to the …

Streptococcus lactarius MB622 and Streptococcus salivarius MB620 isolated from human milk reduce chemokine IL-8 production in response to TNF-α in Caco-2 cell …

A Saeed, A Yasmin, M Baig, MA Ahmed - Cytokine, 2023 - Elsevier
Streptococci are a predominant genera of the human milk microbiome. Among different
lactic acid bacteria (LAB) a few Streptococcal strains are also considered as probiotics …