Osteoarthritis (OA) is a chronic degenerative joint disorder that leads to disability and affects
more than 500 million population worldwide. OA was believed to be caused by the wearing …

Chronic pain exerts an enormous personal and economic burden, affecting more than 30%
of people worldwide according to some studies. Unlike acute pain, which carries survival …

Objective To estimate systematic and anatomic site–specific age‐standardized prevalence
rates (ASRs) and analyze the secular trends of osteoarthritis (OA) at global, regional, and …

Importance Osteoarthritis (OA) is the most common joint disease, affecting an estimated
more than 240 million people worldwide, including an estimated more than 32 million in the …

Importance Most clinical guidelines do not recommend platelet-rich plasma (PRP) for knee
osteoarthritis (OA) because of lack of high-quality evidence on efficacy for symptoms and …

Osteoarthritis (OA) remains the most challenging arthritic disorder, with a high burden of
disease and no available disease-modifying treatments. Symptomatic early-stage OA of the …

Osteoarthritis (OA) is a degenerative and chronic joint disease characterized by clinical
symptoms and distortion of joint tissues. It primarily damages joint cartilage, causing pain …

Objective To assess the effectiveness and safety of different preparations and doses of non-
steroidal anti-inflammatory drugs (NSAIDs), opioids, and paracetamol for knee and hip …

Background Osteoarthritis is the most common form of arthritis in adults, characterised by
chronic pain and loss of mobility. Osteoarthritis most frequently occurs after age 40 years …

Knee osteoarthritis (OA) is a heterogeneous disease associated with substantial effects on
quality of life, and its clinical management is difficult. Among the several available guidelines …