Pancreatic ductal adenocarcinoma (PDAC) is a highly heterogeneous tumor comprising
pancreatic cancer cells, fibroblasts, immune cells, vascular epithelial cells, and other cells in …

Introduction Pancreas ductal adenocarcinoma (PDAC) is a frequently lethal malignancy that
poses unique therapeutic challenges. The current mainstay of therapy for metastatic PDAC …

Gastrointestinal (GI) tumors are a significant global health threat, with high rates of morbidity
and mortality. Exosomes contain various biologically active molecules like nucleic acids …

Pancreatic cancer (PC), a disease with high heterogeneity and a dense stromal
microenvironment, presents significant challenges and a bleak prognosis. Recent …

This comprehensive review delves into the complex interplay between mitochondrial gene
defects and pancreatic cancer pathogenesis through a multiomics approach. By …

Efficient intratumoral penetration is essential for nanomedicine to eradicate pancreatic
tumors. Although nanomedicine can enter the perivascular space of pancreatic tumors, their …

Introduction Pancreatic ductal adenocarcinoma (PDAC), the most common form of
pancreatic cancer, is a particularly lethal disease that is often diagnosed late and is …

Despite the efforts, pancreatic ductal adenocarcinoma (PDAC) is still highly lethal.
Therapeutic challenges reside in late diagnosis and establishment of peculiar tumor …

Simple Summary Pancreatic ductal adenocarcinoma (PDAC) is one of the leading causes of
cancer deaths in the United States due to its late-stage diagnosis. Currently, there are no …

Simple Summary In this study, a rat model of pancreatic ductal adenocarcinoma (PDAC)
was established and extensively analyzed. The histological examination confirmed that the …