Immune activation, inflammation, and non-AIDS co-morbidities in HIV-infected patients under long-term ART
Despite effective antiretroviral therapy (ART), people living with HIV (PLWH) still present
persistent chronic immune activation and inflammation. This condition is the result of several …
persistent chronic immune activation and inflammation. This condition is the result of several …
Epicardial adipose tissue may mediate deleterious effects of obesity and inflammation on the myocardium
M Packer - Journal of the American College of Cardiology, 2018 - jacc.org
Epicardial adipose tissue has unique properties that distinguish it from other depots of
visceral fat. Rather than having distinct boundaries, the epicardium shares an unobstructed …
visceral fat. Rather than having distinct boundaries, the epicardium shares an unobstructed …
Dolutegravir plus two different prodrugs of tenofovir to treat HIV
WDF Venter, M Moorhouse, S Sokhela… - … England Journal of …, 2019 - Mass Medical Soc
Background Two drugs under consideration for inclusion in antiretroviral therapy (ART)
regimens for human immunodeficiency virus (HIV) infection are dolutegravir (DTG) and …
regimens for human immunodeficiency virus (HIV) infection are dolutegravir (DTG) and …
HIV and antiretroviral therapy-related fat alterations
Early in the HIV epidemic, lipodystrophy, characterized by subcutaneous fat loss
(lipoatrophy), with or without central fat accumulation (lipohypertrophy), was recognized as a …
(lipoatrophy), with or without central fat accumulation (lipohypertrophy), was recognized as a …
Metabolic complications affecting adipose tissue, lipid and glucose metabolism associated with HIV antiretroviral treatment
C Lagathu, V Béréziat, J Gorwood… - Expert opinion on …, 2019 - Taylor & Francis
Introduction: Efficient antiretroviral-treatment (ART) generally allows control of HIV infection.
However, persons-living-with-HIV (PLWH), when aging, present a high prevalence of …
However, persons-living-with-HIV (PLWH), when aging, present a high prevalence of …
The impact of weight gain during HIV treatment on risk of pre-diabetes, diabetes mellitus, cardiovascular disease, and mortality
S Kumar, K Samaras - Frontiers in endocrinology, 2018 - frontiersin.org
Since the introduction of combined antiretroviral therapy (cART) and more effective
treatments for AIDS, there has been a dramatic shift from the weight loss and wasting that …
treatments for AIDS, there has been a dramatic shift from the weight loss and wasting that …
Weight gain after HIV therapy initiation: pathophysiology and implications
NC Chandiwana, MJ Siedner… - The Journal of …, 2024 - academic.oup.com
Rapid advances in the potency, safety, and availability of modern HIV antiretroviral therapy
(ART) have yielded a near-normal life expectancy for most people living with HIV (PLWH) …
(ART) have yielded a near-normal life expectancy for most people living with HIV (PLWH) …
Expert panel review on nonalcoholic fatty liver disease in persons with human immunodeficiency virus
Nonalcoholic fatty liver disease (NAFLD) affects 25% of adults in the general population and
is a disease spectrum ranging from steatosis to nonalcoholic steatohepatitis (NASH) to end …
is a disease spectrum ranging from steatosis to nonalcoholic steatohepatitis (NASH) to end …
Insulin resistance in HIV-patients: causes and consequences
MN Pedro, GZ Rocha, D Guadagnini… - Frontiers in …, 2018 - frontiersin.org
Here we review how immune activation and insulin resistance contribute to the metabolic
alterations observed in HIV-infected patients, and how these alterations increase the risk of …
alterations observed in HIV-infected patients, and how these alterations increase the risk of …
A review of chronic comorbidities in adults living with HIV: state of the science
People living with HIV are living longer, high-quality lives; however, as they age, this
population is at increased risk for developing chronic comorbidities, including …
population is at increased risk for developing chronic comorbidities, including …