Junctional adhesion molecules (JAMs) are cell-cell adhesion molecules of the
immunoglobulin superfamily and are involved in the regulation of diverse atherosclerosis …

In Pseudomonas aeruginosa, cell–cell communication based on acyl-homoserine lactone
(HSL) quorum sensing molecules is known to coordinate the production of virulence factors …

Manganese is a trace element that is an essential co-factor in many enzymes critical to
diverse biological pathways. However, excess Mn 2+ leads to neurotoxicity, with psychiatric …

Tight junctions of hepatocytes play crucial roles in the barrier to keep bile in bile canaliculi
away from the blood circulation, which we call the bloodbilliary-barrier (Kojima et al., 2003) …

The polarization of hepatocytes involves formation of functionally distinct sinusoidal
(basolateral) and bile canalicular (apical) plasma membrane domains that are separated by …

The correct functioning of hepatocytes requires the establishment and maintenance of
hepatocyte polarity. However, the mechanisms regulating the generation of hepatocyte …

Claudin-16 is involved in the paracellular reabsorption of Mg2+ in the thick ascending limb
of Henle. Little is known about the mechanism regulating the tight junctional localization of …

Background Information Hepatocytes, which perform the main functions of the liver, are
particularly vulnerable to toxic agents such as cadmium, an environmental pollutant. To …

The purpose of this study was to develop a method to comprehensively determine the
localization of apical and basolateral membrane proteins, using a combination of …

Tight junctions (TJs) of cells expressing simple epithelial polarity have been extensively
studied, but less is known about TJs of cells expressing complex polarity. In this paper we …