Cancer is a multistage process resulting in an uncontrolled and abrupt division of cells and
is one of the leading causes of mortality. The cases reported and the predictions for the near …

Natural product libraries contain specialized metabolites derived from plants, animals, and
microorganisms that play a pivotal role in drug discovery due to their immense structural …

Natural products (NPs) are important sources of clinical drugs due to their structural diversity
and biological prevalidation. However, the structural complexity of NPs leads to synthetic …

Cancer is one of the largest causes of morbimortality in the world and due to its prevalence
the discovery of novel anticancer drugs in of great importance. The past century brought …

Currently, HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs) are a major
component of the highly active anti-retroviral therapy (HAART) regimen. However, the …

Worldwide cancer incidence and mortality have always been a concern to the community.
The cancer mortality rate has generally declined over the years; however, there is still an …

With cancer incidence rates continuing to increase and occurrence of resistance in drug
treatment, there is a pressing demand to find safer and more effective anticancer strategy for …

Abstract 1, 2, 3, 4-Tetrahydro-β-carboline (THβC) scaffold is widespread in many natural
products (NPs) and synthetic compounds which show a variety of pharmacological activities …

To date, effectively controlling resistant weeds has been a great challenge in modern
agricultural production. Developing new modes of action of herbicides would be an efficient …

Exploration of structurally novel natural products greatly facilitates the discovery of
biologically active pharmacophores that are biologically validated starting points for the …