[HTML][HTML] Ikaros fingers on lymphocyte differentiation
T Yoshida, K Georgopoulos - International journal of hematology, 2014 - Springer
The Ikaros family of DNA-binding proteins are critical regulators of lymphocyte
differentiation. In multipotent, hematopoietic progenitors, Ikaros supports transcriptional …
differentiation. In multipotent, hematopoietic progenitors, Ikaros supports transcriptional …
Genetic abnormalities associated with acute lymphoblastic leukemia
T Yokota, Y Kanakura - Cancer science, 2016 - Wiley Online Library
Acute lymphoblastic leukemia (ALL) occurs with high frequency in childhood and is
associated with high mortality in adults. Recent technical advances in next‐generation …
associated with high mortality in adults. Recent technical advances in next‐generation …
[HTML][HTML] Early B lymphocyte development: Similarities and differences in human and mouse
M Ichii, K Oritani, Y Kanakura - World journal of stem cells, 2014 - ncbi.nlm.nih.gov
B lymphocytes differentiate from hematopoietic stem cells through a series of distinct stages.
Early B cell development proceeds in bone marrow until immature B cells migrate out to …
Early B cell development proceeds in bone marrow until immature B cells migrate out to …
ZNF423 and ZNF521: EBF1 antagonists of potential relevance in B‐lymphoid malignancies
The development of the B‐lymphoid cell lineage is tightly controlled by the concerted action
of a network of transcriptional and epigenetic regulators. EBF1, a central component of this …
of a network of transcriptional and epigenetic regulators. EBF1, a central component of this …
[HTML][HTML] Role of tissue-specific AT-rich DNA sequence-binding proteins in lymphocyte differentiation
T Yokota, Y Kanakura - International journal of hematology, 2014 - Springer
A great many transcription factors, cytokines, and cytokine receptors have been identified as
indispensable elements in lymphocyte differentiation, but the molecular mechanism that …
indispensable elements in lymphocyte differentiation, but the molecular mechanism that …
[HTML][HTML] Histone methylation and V (D) J recombination
N Shimazaki, MR Lieber - International journal of hematology, 2014 - Springer
Abstract V (D) J recombination is the process by which the diversity of antigen receptor
genes is generated and is also indispensable for lymphocyte development. This …
genes is generated and is also indispensable for lymphocyte development. This …
[HTML][HTML] Small RNA as a regulator of hematopoietic development, immune response in infection and tumorigenesis
K Okuyama, J Ogata, N Yamakawa, B Chanda… - International journal of …, 2014 - Springer
Posttranscriptional gene regulation by small RNAs (15–40-nucleotide noncoding RNAs) is
now established as an important branch of the gene regulatory system. It has recently been …
now established as an important branch of the gene regulatory system. It has recently been …
[HTML][HTML] Identification of osteoblast stimulating factor 5 as a negative regulator in the B-lymphopoietic niche
N Fujita, M Ichii, T Maeda, N Saitoh, T Yokota… - Experimental …, 2015 - Elsevier
Recent studies have revealed the crucial role of the niche which supports B-lymphocyte
differentiation from hematopoietic stem cells. In this study, we aimed to identify a novel …
differentiation from hematopoietic stem cells. In this study, we aimed to identify a novel …
Cancer immunotherapy
LM Messina, G Tie - US Patent 10,034,901, 2018 - Google Patents
US10034901B2 - Cancer immunotherapy - Google Patents US10034901B2 - Cancer
immunotherapy - Google Patents Cancer immunotherapy Download PDF Info Publication …
immunotherapy - Google Patents Cancer immunotherapy Download PDF Info Publication …