Tumor suppressor p16INK4a − modulator of glycomic profile and galectin‐1 expression to increase susceptibility to carbohydrate‐dependent induction of anoikis in …
S André, H Sanchez‐Ruderisch, H Nakagawa… - The FEBS …, 2007 - Wiley Online Library
Expression of the tumor suppressor p16INK4a after stable transfection can restore the
susceptibility of epithelial tumor cells to anoikis. This property is linked to increases in the …
susceptibility of epithelial tumor cells to anoikis. This property is linked to increases in the …
Homodimeric galectin-7 (p53-induced gene 1) is a negative growth regulator for human neuroblastoma cells
J Kopitz, S Andre, C Von Reitzenstein, K Versluis… - Oncogene, 2003 - nature.com
The extracellular functions of galectin-7 (p53-induced gene 1) are largely unknown. On the
surface of neuroblastoma cells (SK-N-MC), the increased GM 1 density, a result of …
surface of neuroblastoma cells (SK-N-MC), the increased GM 1 density, a result of …
Persubstituted cyclodextrin-based glycoclusters as inhibitors of protein− carbohydrate recognition using purified plant and mammalian lectins and wild-type and lectin …
S André, H Kaltner, T Furuike, SI Nishimura… - Bioconjugate …, 2004 - ACS Publications
Multivalent glycoclusters have the potential to become pharmaceuticals by virtue of their
target specificity toward clinically relevant sugar receptors. Their application can also …
target specificity toward clinically relevant sugar receptors. Their application can also …
Tumor galectinology: insights into the complex network of a family of endogenous lectins
H Lahm, S André, A Hoeflich, H Kaltner… - Glycoconjugate …, 2003 - Springer
Abstract β-Galactosides of cell surface glycoconjugates are docking sites for endogenous
lectins of the galectin family. In cancer cells, primarily galectins-1 and-3 have been studied …
lectins of the galectin family. In cancer cells, primarily galectins-1 and-3 have been studied …
Cell surface glycans: the why and how of their functionality as biochemical signals in lectin-mediated information transfer
HJ Gabius - Critical Reviews™ in Immunology, 2006 - dl.begellhouse.com
Calculations of the coding capacity of biomolecules come up with the striking result that
carbohydrates excel nucleotides and amino acids by far in this respect. Consequently …
carbohydrates excel nucleotides and amino acids by far in this respect. Consequently …
Glycosyldisulfides from dynamic combinatorial libraries as O-glycoside mimetics for plant and endogenous lectins: their reactivities in solid-phase and cell assays and …
S André, Z Pei, HC Siebert, O Ramström… - Bioorganic & medicinal …, 2006 - Elsevier
Dynamic combinatorial library design exploiting the thiol–disulfide exchange readily affords
access to glycosyldisulfides. In order to reveal lectin-binding properties of this type of non …
access to glycosyldisulfides. In order to reveal lectin-binding properties of this type of non …
Rigidified multivalent lactose molecules and their interactions with mammalian galectins: a route to selective inhibitors
I Vrasidas, S André, P Valentini, C Böck… - Organic & …, 2003 - pubs.rsc.org
New and rigid multivalent lactose molecules were prepared. The structures contain lactose-
2-aminothiazoline units at the periphery that were formed from a cyclisation of the thiourea …
2-aminothiazoline units at the periphery that were formed from a cyclisation of the thiourea …
Unique Conformer Selection of Human Growth-Regulatory Lectin Galectin-1 for Ganglioside GM1 versus Bacterial Toxins,
HC Siebert, S André, SY Lu, M Frank, H Kaltner… - Biochemistry, 2003 - ACS Publications
Endogenous lectins induce effects on cell growth by binding to antennae of natural
glycoconjugates. These complex carbohydrates often present more than one potential lectin …
glycoconjugates. These complex carbohydrates often present more than one potential lectin …
Galectin-1 and galectin-3 in fetal development of bovine respiratory and digestive tracts: comparison of cell type-specific expression profiles and subcellular …
H Kaltner, K Seyrek, A Heck, F Sinowatz… - Cell and tissue …, 2002 - Springer
Histochemical monitoring of developmental processes is presently centered on protein-
protein interactions. However, oligosaccharides have the potential to store and transmit …
protein interactions. However, oligosaccharides have the potential to store and transmit …
A guide to signaling pathways connecting protein-glycan interaction with the emerging versatile effector functionality of mammalian lectins
A Villalobo, A Nogales-González… - Trends in Glycoscience …, 2006 - jstage.jst.go.jp
抄録 細胞膜は細胞と外部環境との間のコミュニケーションのためのインターフェイスとしてゆるぎ
ない役割をもつ. したがって外部シグナルに対する細胞の反応性や応答能力は, 細胞表面の決定基 …
ない役割をもつ. したがって外部シグナルに対する細胞の反応性や応答能力は, 細胞表面の決定基 …