Interaction profile of galectin-5 with free saccharides and mammalian glycoproteins: probing its fine specificity and the effect of naturally clustered ligand presentation

AM Wu, T Singh, JH Wu, M Lensch, S André… - …, 2006 - academic.oup.com
Cell-surface glycans are functional docking sites for tissue lectins such as the members of
the galectin family. This interaction triggers a wide variety of responses; hence, there is a …

Identification of peptide ligands for malignancy-and growth-regulating galectins using random phage-display and designed combinatorial peptide libraries

S André, CJ Arnusch, I Kuwabara, R Russwurm… - Bioorganic & medicinal …, 2005 - Elsevier
Members of the galectin family of endogenous lectins are involved in tumor growth
regulation and in establishing characteristics of the malignant phenotype via protein …

Glycomic profiling of developmental changes in bovine testis by lectin histochemistry and further analysis of the most prominent alteration on the level of the …

JC Manning, K Seyrek, H Kaltner, S André… - Histology and …, 2004 - digitum.um.es
The emerging concept of the sugar code attributes functional significance to
oligosaccharides of cellular glycoconjugates by protein (lectin)-carbohydrate interactions …

Detection of S100B, S100A6 and galectin-3 ligands in meningiomas as markers of aggressiveness

S Hancq, I Salmon, J Brotchi… - International …, 2004 - spandidos-publications.com
The biological factors responsible for the increased aggressiveness in atypical
meningiomas are not well known. The aim of this study is to evaluate the discriminatory …

Morphological, glycohistochemical, and immunohistochemical studies on the embryonic and adult bovine testis

A Abd-Elmaksoud - 2005 - edoc.ub.uni-muenchen.de
In the present study, the testes of 32 bovine embryos with different crown-rump length (2.5-
90 cm CRL) and of 15 sexually mature bulls (Deutsches Fleckvieh) were investigated using …

Interference of the galactose-dependent binding of lectins by novel pentapeptide ligands

CJ Arnusch, S André, P Valentini, M Lensch… - Bioorganic & medicinal …, 2004 - Elsevier
A library of pentapeptides containing the sequence–Y–X–Y–based on rational design was
screened with six different lectins. Sequences were identified that modulate galectin binding …

Carbohydrate Chain of Ganglioside GM1 as a Ligand: Identification of the Binding Strategies of Three 15 mer Peptides and Their Divergence from the Binding Modes …

HC Siebert, K Born, S André, M Frank… - … A European Journal, 2006 - Wiley Online Library
The branched pentasaccharide chain of ganglioside GM1 is a prominent cell surface ligand,
for example, for cholera toxin or tumor growth‐regulatory homodimeric galectins. This …

Diagnostic relevance of Langerin detection in cells from bronchoalveolar lavage of patients with pulmonary Langerhans cell histiocytosis, sarcoidosis and idiopathic …

K Smetana, O Měřička, S Saeland, J Homolka… - Virchows Archiv, 2004 - Springer
The diagnosis of pulmonary Langerhans cell histiocytosis might be refined by demonstrating
reliability of a new cell marker, ie, Langerin (CD207), used on bronchoalveolar lavage fluid …

Analysis of Protein− Carbohydrate Interaction at the Lower Size Limit of the Protein Part (15-Mer Peptide) by NMR Spectroscopy, Electrospray Ionization Mass …

HC Siebert, SY Lü, M Frank, J Kramer… - Biochemistry, 2002 - ACS Publications
Structural analysis of minimally sized lectins will offer insights into fundamentals of
intermolecular recognition and potential for biomedical applications. We thus moved …

Primary colorectal carcinomas and their intrapulmonary metastases: Clinical, glyco‐, immuno‐and lectin histochemical, nuclear and syntactic structure analysis with …

K Kayser, S Zink, S André, MP Schüring, E Hecker… - Apmis, 2002 - Wiley Online Library
Background. The aim of the study was to correlate clinical factors (disease‐free
interval/survival) with growth pattern in terms of structural entropy of patients with primary …