Accelerated aging in serious mental disorders
FS Bersani, SH Mellon, VI Reus… - Current Opinion in …, 2019 - journals.lww.com
We define and discuss several proposed biological aging markers that have been examined
in SMDs, we review the most recent findings, and we conclude with opinions regarding the …
in SMDs, we review the most recent findings, and we conclude with opinions regarding the …
Frailty Index as a clinical measure of biological age in psychiatry
Background Serious mental illnesses may be characterized by accelerated biological aging,
and over the last years the research on the topic has been stimulated by studies exploring …
and over the last years the research on the topic has been stimulated by studies exploring …
PTSD, major depression, and advanced transcriptomic age in brain tissue
Background Psychiatric disorders have been associated with advanced epigenetic age in
DNA methylation, yet this relationship has not been studied in the brain transcriptome. We …
DNA methylation, yet this relationship has not been studied in the brain transcriptome. We …
Differences in telomere length between patients with bipolar disorder and controls are influenced by lithium treatment
Aim: To assess the role of lithium treatment in the relationship between bipolar disorder (BD)
and leukocyte telomere length (LTL). Materials & methods: We compared LTL between 131 …
and leukocyte telomere length (LTL). Materials & methods: We compared LTL between 131 …
Telomere length and psychopathology: specificity and direction of effects within the Bucharest Early Intervention Project
Objective Telomere length (TL) has been linked to several psychiatric conditions in children
and adults. Telomere shortening is accelerated by early adversity, including maltreatment …
and adults. Telomere shortening is accelerated by early adversity, including maltreatment …
Intergenerational effects of maternal lifetime stressor exposure on offspring telomere length in Black and White women
BackgroundAlthough maternal stressor exposure has been associated with shorter telomere
length (TL) in offspring, this literature is based largely on White samples. Furthermore, timing …
length (TL) in offspring, this literature is based largely on White samples. Furthermore, timing …
Telomere length and epigenetic age acceleration in adolescents with anxiety disorders
A Cerveira de Baumont, MS Hoffmann, A Bortoluzzi… - Scientific reports, 2021 - nature.com
Evidence on the relationship between genetics and mental health are flourishing. However,
few studies are evaluating early biomarkers that might link genes, environment, and …
few studies are evaluating early biomarkers that might link genes, environment, and …
Interpersonal-level discrimination indices, sociodemographic factors, and telomere length in African-Americans and Whites
Objective Studies have linked self-reported discrimination to telomere attrition, a biological
marker of accelerated cellular aging. However, it is unknown whether intersections between …
marker of accelerated cellular aging. However, it is unknown whether intersections between …
[HTML][HTML] Assessing the contributions of childhood maltreatment subtypes and depression case-control status on telomere length reveals a specific role of physical …
Background Studies have provided evidence that both childhood maltreatment and
depressive disorders are associated with shortened telomere lengths. However, as …
depressive disorders are associated with shortened telomere lengths. However, as …
Prospective association between major depressive disorder and leukocyte telomere length over two years
MC Vance, E Bui, SS Hoeppner, B Kovachy… - …, 2018 - Elsevier
Background Reduced leukocyte telomere length (LTL) has been found to be associated with
multiple common age-related diseases, including heart disease, diabetes, and cancer. A link …
multiple common age-related diseases, including heart disease, diabetes, and cancer. A link …