Accelerated brain aging in patients with obsessive-compulsive disorder

L Liu, J Liu, L Yang, B Wen, X Zhang, J Cheng… - Frontiers in …, 2022 - frontiersin.org
Obsessive-compulsive disorder (OCD) may be accompanied by an accelerated structural
decline of the brain with age compared to healthy controls (HCs); however, this has yet to be …

Telomere length in psychiatric disorders: Is it more than an ageing marker?

N Monroy-Jaramillo, E Dyukova… - The World Journal of …, 2018 - Taylor & Francis
Objectives: Psychiatric and substance-use disorders have been associated with premature
biological ageing. Telomere length (TL), considered an ageing marker, has been analysed …

Biological Aging Acceleration Due to Environmental Exposures: An Exciting New Direction in Toxicogenomics Research

S Dutta, JM Goodrich, DC Dolinoy, DM Ruden - Genes, 2023 - mdpi.com
Biological clock technologies are designed to assess the acceleration of biological age (B-
age) in diverse cell types, offering a distinctive opportunity in toxicogenomic research to …

[HTML][HTML] Telomere length associations with clinical diagnosis, age, and polygenic risk scores for anxiety disorder, depression, and bipolar disorder

J Mutz, CM Lewis - Biological Psychiatry Global Open Science, 2023 - Elsevier
Background Accelerated biological aging might contribute to the lower life expectancy of
individuals with mental disorders. The aim of this study was to characterize telomere length …

Aging biological markers in a cohort of antipsychotic-naïve first-episode psychosis patients

F Talarico, G Xavier, VK Ota, LM Spindola… - …, 2021 - Elsevier
Schizophrenia is a severe and multifactorial disorder with an unknown causative
pathophysiology. Abnormalities in neurodevelopmental and aging processes have been …

The implications of war captivity and long-term psychopathology trajectories for telomere length

Z Solomon, N Tsur, Y Levin, O Uziel, M Lahav… - …, 2017 - Elsevier
Background Previous findings have demonstrated the link between trauma, its
psychopathological aftermath and cellular aging, as reflected in telomere length. However …

The potential impact of biochemical mediators on telomere attrition in major depressive disorder and implications for future study designs: a narrative review

A Manoliu, OG Bosch, J Brakowski, AB Brühl… - Journal of affective …, 2018 - Elsevier
Background Major depressive disorder (MDD) has been proposed to represent a “disease of
premature aging”, which is associated with certain biomarkers of cellular ageing and …

Weight loss maintenance and cellular aging in the supporting health through nutrition and exercise study

AE Mason, FM Hecht, JJ Daubenmier… - Psychosomatic …, 2018 - journals.lww.com
Objective The aim of the study was to determine, within a weight loss clinical trial for obesity,
the impact of intervention arm, weight change, and weight loss maintenance on telomere …

Leukocyte telomere length is reduced in patients with major depressive disorder

C Pisanu, EE Tsermpini, M Skokou… - Drug development …, 2020 - Wiley Online Library
Major depressive disorder (MDD) is a chronic, severe psychiatric illness with an incidence of
3% worldwide. MDD patients have a significantly impaired quality of life and reduced life …

Perceived stress, depressive symptoms, and oxidative DNA damage

C Shimanoe, M Hara, Y Nishida, H Nanri… - Psychosomatic …, 2018 - journals.lww.com
Objective Psychosocial stress may influence the risk of disease through its association with
oxidative DNA damage. We examined whether perceived stress and depressive symptoms …