Abstract Concepts of cognitive control (CC) and executive function (EF) are defined in terms
of their relationships with goal-directed behavior versus habits and controlled versus …

Noradrenergic and cholinergic systems are among the most vulnerable brain systems in
neuropsychiatric diseases of ageing, including Alzheimer's disease, Parkinson's disease …

The granular dorsolateral prefrontal cortex (dlPFC) is an evolutionary specialization of
primates that is centrally involved in cognition. We assessed more than 600,000 single …

Sleep interacts reciprocally with immune system activity, but its specific relationship with
microglia—the resident immune cells in the brain—remains poorly understood. Here, we …

Foraging theory prescribes when optimal foragers should leave the current option for more
rewarding alternatives. Actual foragers often exploit options longer than prescribed by the …

The noradrenaline (NA) system is one of the brain's major neuromodulatory systems; it
originates in a small midbrain nucleus, the locus coeruleus (LC), and projects widely …

It is well established that acute moderate-intensity exercise improves cognitive performance.
However, the effects of acute high-intensity aerobic exercise on cognitive performance have …

Abstract Changes in dopaminergic neuromodulation play a key role in adult memory
decline. Recent research has also implicated noradrenaline in shaping late-life memory …

Synaptic plasticity configures interactions between neurons and is therefore likely to be a
primary driver of behavioral learning and development. How this microscopic-macroscopic …

Neuroinflammatory disorders preferentially impair the higher cognitive and executive
functions of the prefrontal cortex (PFC). This includes such challenging disorders as …