Epigenome-wide association studies: current knowledge, strategies and recommendations
The aetiology and pathophysiology of complex diseases are driven by the interaction
between genetic and environmental factors. The variability in risk and outcomes in these …
between genetic and environmental factors. The variability in risk and outcomes in these …
Air pollution and DNA methylation: effects of exposure in humans
CF Rider, C Carlsten - Clinical epigenetics, 2019 - Springer
Air pollution exposure is estimated to contribute to approximately seven million early deaths
every year worldwide and more than 3% of disability-adjusted life years lost. Air pollution …
every year worldwide and more than 3% of disability-adjusted life years lost. Air pollution …
Crop breeding chips and genotyping platforms: progress, challenges, and perspectives
There is a rapidly rising trend in the development and application of molecular marker
assays for gene mapping and discovery in field crops and trees. Thus far, more than 50 SNP …
assays for gene mapping and discovery in field crops and trees. Thus far, more than 50 SNP …
DNA methylation clocks and their predictive capacity for aging phenotypes and healthspan
T Bergsma, E Rogaeva - Neuroscience insights, 2020 - journals.sagepub.com
The number of age predictors based on DNA methylation (DNAm) profile is rising due to
their potential in predicting healthspan and application in age-related illnesses, such as …
their potential in predicting healthspan and application in age-related illnesses, such as …
methylclock: a Bioconductor package to estimate DNA methylation age
D Pelegí-Sisó, P De Prado, J Ronkainen… - …, 2021 - academic.oup.com
Motivation Ageing is a biological and psychosocial process related to diseases and
mortality. It correlates with changes in DNA methylation (DNAm) in all human tissues …
mortality. It correlates with changes in DNA methylation (DNAm) in all human tissues …
Epigenome-wide meta-analysis of DNA methylation differences in prefrontal cortex implicates the immune processes in Alzheimer's disease
DNA methylation differences in Alzheimer's disease (AD) have been reported. Here, we
conducted a meta-analysis of more than 1000 prefrontal cortex brain samples to prioritize …
conducted a meta-analysis of more than 1000 prefrontal cortex brain samples to prioritize …
Recent progress, methods and perspectives in forensic epigenetics
A Vidaki, M Kayser - Forensic Science International: Genetics, 2018 - Elsevier
Forensic epigenetics, ie, investigating epigenetics variation to resolve forensically relevant
questions unanswerable with standard forensic DNA profiling has been gaining substantial …
questions unanswerable with standard forensic DNA profiling has been gaining substantial …
Systematic evaluation of DNA methylation age estimation with common preprocessing methods and the Infinium MethylationEPIC BeadChip array
Background The capacity of technologies measuring DNA methylation (DNAm) is rapidly
evolving, as are the options for applicable bioinformatics methods. The most commonly used …
evolving, as are the options for applicable bioinformatics methods. The most commonly used …
Differential DNA methylation in experienced meditators after an intensive day of mindfulness-based practice: Implications for immune-related pathways
The human methylome is dynamically influenced by psychological stress. However, its
responsiveness to stress management remains underexplored. Meditation practice has …
responsiveness to stress management remains underexplored. Meditation practice has …
Distinct CSF biomarker-associated DNA methylation in Alzheimer's disease and cognitively normal subjects
W Zhang, JI Young, L Gomez, MA Schmidt… - Alzheimer's research & …, 2023 - Springer
Background Growing evidence has demonstrated that DNA methylation (DNAm) plays an
important role in Alzheimer's disease (AD) and that DNAm differences can be detected in the …
important role in Alzheimer's disease (AD) and that DNAm differences can be detected in the …