Actinobacteria constitute a highly diverse bacterial phylum with an unrivalled metabolic
versatility. They produce most of the clinically used antibiotics and a plethora of other natural …

Major losses of crop yield and quality caused by soil-borne plant diseases have long
threatened the ecology and economy of agriculture and forestry. Biological control using …

Bacterial secondary metabolites are a major source of antibiotics and other bioactive
compounds. In microbial communities, these molecules can mediate interspecies …

Soils suppressive to soilborne pathogens have been identified worldwide for almost 60
years and attributed mainly to suppressive or antagonistic microorganisms. Rather than …

Microbes are typically surrounded by different strains and species with whom they compete
for scarce nutrients and limited space. Given such challenging living conditions, microbes …

The spatial organization of complex natural microbiomes is critical to understanding the
interactions of the individual taxa that comprise a community. Although the revolution in DNA …

The rich diversity of secondary metabolites produced by soil bacteria has been appreciated
for over a century, and advances in chemical analysis and genome sequencing continue to …

Actinomycetes are a diverse family of filamentous bacteria that produce a plethora of natural
products relevant for agriculture, biotechnology and medicine, including the majority of the …

Phytopathogenic fungi, causing significant economic and production losses, are becoming a
serious threat to global food security. Due to an increase in fungal resistance and the …

Microbial secondary metabolites (MSMs) have played and continue to play a highly
significant role in the drug discovery and development process. Genetically, MSM chemical …