Neurological disorders pose a significant burden on individuals and society, affecting
millions worldwide. These disorders, including but not limited to Alzheimer's disease …

Sex-specific differences in biology and physiology likely start at the time of conception and
progress and mature during the pre-puberty time frame and then during the transitions …

Neuromyelitis optica (NMO) was long considered a clinical variant of multiple sclerosis (MS).
However, the discovery of a novel and pathogenic anti-astrocytic serum autoantibody …

The socio-economic impact of diseases associated with cognitive impairment is increasing.
According to the Alzheimer's Society there are over 850,000 people with dementia in the UK …

The blood-spinal cord barrier (BSCB) has been long thought of as a functional equivalent to
the blood-brain barrier (BBB), restricting blood flow into the spinal cord. The spinal cord is …

The neurovascular unit (NVU) of the brain is composed of multiple cell types that act
synergistically to modify blood flow to locally match the energy demand of neural activity, as …

Focused ultrasound combined with circulating microbubbles (FUS+ MB) can transiently
enhance blood-brain barrier (BBB) permeability at targeted brain locations. Its great promise …

The central nervous system (CNS) has specific barriers that protect the brain from potential
threats and tightly regulate molecular transport. Despite the critical functions of the CNS …

Glioblastoma is one of the central nervous system most aggressive and lethal cancers with
poor overall survival rate. Systemic treatment of glioblastoma remains the most challenging …

The maintenance of adequate blood supply and vascular integrity is fundamental to ensure
cerebral function. A wide range of studies report vascular dysfunction in white matter …