Exosomes are nanovesicles with a wide range of chemical compositions used in many
different applications. Mesenchymal stem cell-derived exosomes (MSCs-EXOs) are …

Osteoarthritis (OA) is one of the most common diseases leading to physical disability, with
age being the main risk factor, and degeneration of articular cartilage is the main focus for …

Osteoarthritis is a prevalent joint disease that significantly affects the daily life of the elderly
and is one of the primary causes of disability in this population. This study aims to evaluate …

Osteoarthritis (OA), as a degenerative disease, leads to high socioeconomic burdens and
disability rates. The knee joint is typically the most affected and is characterized by …

Mesenchymal stem cells (MSCs) have shown chondroprotective effects in cartilage repair.
However, side effects caused by MSC treatment limit their application in clinic. As a cell‐free …

Autophagy is an intracellular degradation system that maintains the stable state of cell
energy metabolism. Some recent findings have indicated that autophagy dysfunction is an …

Mesenchymal stem cells (MSCs) are widely distributed pluripotent stem cells with powerful
immunomodulatory capacity. MSCs transplantation therapy (MSCT) is widely used in the …

Autophagy, as a fundamental mechanism for cellular homeostasis, is generally involved in
the occurrence and progression of various diseases. Osteoarthritis (OA) is the most common …

Osteoarthritis (OA) is a chronic joint disease characterized by articular cartilage
degeneration, secondary bone hyperplasia, inadequate extracellular matrix synthesis and …

Bone metabolic diseases have been tormented and are plaguing people worldwide due to
the lack of effective and thorough medical interventions and the poor understanding of their …