Autophagy is a highly conserved catabolic process and participates in a variety of cellular
biological activities. The phosphoinositide 3-kinase (PI3K)/protein kinase B …

The current challenges in cancer treatment using conventional therapies have made the
emergence of nanotechnology with more advancements. The exponential growth of …

Oncogenic KRAS mutation-driven pancreatic ductal adenocarcinoma is currently the fourth-
leading cause of cancer-related deaths in the United States. Macroautophagy (hereafter …

Conspectus The naphthylisoquinoline (NIQ) alkaloids are a thrilling class of natural biaryls─
structurally, biosynthetically, and pharmacologically. A common feature of these metabolites …

Natural products represent a paramount source of novel drugs. Numerous plant-derived
natural products have demonstrated potent anti-tumor properties, thereby garnering …

Covering: up to April 2021 During the past decades, a plethora of natural products with
restricted rotation about a biaryl axis have been discovered, among them the …

Breast cancer is one of the most common types of cancer in the world and a major cause of
mortality. Present therapeutic strategies against breast cancer have severe drawbacks such …

Studies in Natural Products Chemistry, Volume 79 covers the synthesis, testing and
recording of the medicinal properties of natural products, providing cutting-edge accounts of …

Pancreatic tumors grow in an “austerity” tumor microenvironment characterized by nutrient
deprivation and hypoxia. This leads to the activation of adaptive pathways in pancreatic …

Covering: up to April 2019 Dimeric naphthylisoquinoline (NIQ) alkaloids are an emerging
group of structurally, biosynthetically, and pharmacologically intriguing natural products, as …