Deficiency in vitamin D (VitD), a lipid-soluble vitamin and steroid hormone, affects
approximately 24% to 40% of the population of the Western world. In addition to its well …

Both cognitive impairment and cardiovascular diseases have a high incidence in the elderly
population, increasing the burden of care and reducing the quality of life. Studies have …

Abstract Ethnopharmacological relevance Dengzhan Xixin injection (DX), a preparation of
extracts from traditional Chinese medicine Erigeron breviscapus (Vaniot) Hand.-Mazz., has …

Introduction: Memory is defined as the ability to store, maintain and retrieve information.
Learning is the acquisition of information that changes behavior and memory. Stress …

From the first described AD case in 1901 to the current year 2022, understanding the
pathogenesis of Alzheimer's disease (AD) and dementia has undergone a long and tortuous …

Abstract Changes in cellular Ca2+ levels have major influences on vascular function and
blood pressure regulation. Vascular smooth muscle cells (SMCs) and endothelial cells …

Diabetes mellitus (DM) is one of the primary pathological factors that contributes to aging-
related cognitive impairments, but the underlying mechanisms remain unclear. We recently …

Alzheimer's disease and Alzheimer's disease–related dementias (AD/ADRD) are associated
with cerebral hypoperfusion or reductions in baseline cerebral blood flow (CBF). The …

Age-related cerebrovascular pathologies, ranging from cerebromicrovascular functional and
structural alterations to large vessel atherosclerosis, promote the genesis of vascular …

Objectives: Diabetes is an independent risk factor for dementia. Mitochondrial dysfunction is
a critical player in diabetes and diabetic complications. The present study aimed to …