[HTML][HTML] Skin pigmentation types, causes and treatment—a review

AM Thawabteh, A Jibreen, D Karaman, A Thawabteh… - Molecules, 2023 - mdpi.com
Human skin pigmentation and melanin synthesis are incredibly variable, and are impacted
by genetics, UV exposure, and some drugs. Patients' physical appearance, psychological …

[HTML][HTML] Brain washing and neural health: role of age, sleep, and the cerebrospinal fluid melatonin rhythm

RJ Reiter, R Sharma, MS Cucielo, DX Tan… - Cellular and Molecular …, 2023 - Springer
The brain lacks a classic lymphatic drainage system. How it is cleansed of damaged
proteins, cellular debris, and molecular by-products has remained a mystery for decades …

Diabetes mellitus and melatonin: Where are we?

R Patel, N Parmar, SP Palit, N Rathwa… - Biochimie, 2022 - Elsevier
Diabetes mellitus (DM) and diabetes-related complications are amongst the leading causes
of mortality worldwide. The international diabetes federation (IDF) has estimated 592 million …

[HTML][HTML] The potential role of melatonin in retarding intervertebral disc ageing and degeneration: a systematic review

Z Cheng, Q Xiang, J Wang, Y Zhang - Ageing Research Reviews, 2021 - Elsevier
Intervertebral disc degeneration (IDD) is a common degenerative disease of the
musculoskeletal system that develops with age. It is regarded as the main cause of chronic …

Tryptophan metabolism and disposition in cancer biology and immunotherapy

AAB Badawy - Bioscience Reports, 2022 - portlandpress.com
Tumours utilise tryptophan (Trp) and its metabolites to promote their growth and evade host
defences. They recruit Trp through up-regulation of Trp transporters, and up-regulate key …

[HTML][HTML] Injectable mesoporous bioactive glass/sodium alginate hydrogel loaded with melatonin for intervertebral disc regeneration

R Wu, L Huang, Q Xia, Z Liu, Y Huang, Y Jiang… - Materials Today Bio, 2023 - Elsevier
Intervertebral disc degeneration (IDD) is a major contributing factor to both lower back and
neck pain. As IDD progresses, the intervertebral disc (IVD) loses its ability to maintain its disc …

[HTML][HTML] Oxidative stress as a possible target in the treatment of toxoplasmosis: perspectives and ambiguities

K Szewczyk-Golec, M Pawłowska… - International journal of …, 2021 - mdpi.com
Toxoplasma gondii is an apicomplexan parasite causing toxoplasmosis, a common disease,
which is most typically asymptomatic. However, toxoplasmosis can be severe and even fatal …

Testing bidirectional, longitudinal associations between disturbed sleep and depressive symptoms in children and adolescents using cross-lagged models

C Marino, B Andrade, J Montplaisir, D Petit… - JAMA Network …, 2022 - jamanetwork.com
Importance Understanding the longitudinal, bidirectional associations between disturbed
sleep and depression in childhood and adolescence is crucial for the development of …

Clinical efficacy and safety of melatonin supplementation in multiple sclerosis: a systematic review

S Morsali, Z Sabahi, J Kakaei, Z Hakimzadeh… - …, 2023 - Springer
Background Melatonin is a neurohormone secreted predominantly by the pineal gland that
is demonstrated to be associated with the pathogenesis of multiple sclerosis (MS). This …

[HTML][HTML] Melatonin as a potential treatment for septic cardiomyopathy

AM Taha, AM Mahmoud, MM Ghonaim… - Biomedicine & …, 2023 - Elsevier
Septic cardiomyopathy (SCM) is a common complication of sepsis contributing to high
mortality rates. Its pathophysiology involves complex factors, including inflammatory …