Pertussis is a highly communicable acute respiratory infection caused by Bordetella
pertussis. Immunity is not lifelong after natural infection or vaccination. Pertussis outbreaks …

Despite high global vaccine coverage, whooping cough, also known as pertussis, caused by
the gram-negative obligate human pathogen Bordetella pertussis (Bp), is resurging …

Vaccines against SARS-CoV-2 that induce mucosal immunity capable of preventing
infection and disease remain urgently needed. In this study, we demonstrate the efficacy of …

Introduction Resurgence of pertussis, caused by Bordetella pertussis, necessitates novel
vaccines and vaccination strategies to combat this disease. Alum-adjuvanted acellular …

Despite high vaccine coverage in many parts of the world, pertussis is resurging in a number
of areas in which acellular vaccines are the primary vaccine administered to infants and …

Pertussis ('whooping cough') is a severe respiratory tract infection that primarily affects
young children and unimmunised infants. Despite widespread vaccine coverage, it remains …

Well-adapted pathogens have evolved to survive the many challenges of a robust immune
response. Defending against all host antimicrobials simultaneously would be exceedingly …

The Bordetella species are Gram-negative bacterial pathogens that colonizes mammalian
respiratory tract causing respiratory diseases in humans and animals. B. bronchiseptica …

Acellular pertussis vaccines protect against severe pertussis, but vaccine-induced immunity
wanes over time. Prior animal studies showed that T-cell responses are integral to long …

Pertussis is a highly contagious respiratory disease caused by the Gram-negative bacterial
pathogen, Bordetella pertussis. Despite high global vaccination rates, pertussis is resurging …