Heart failure with preserved ejection fraction: JACC scientific statement

BA Borlaug, K Sharma, SJ Shah, JE Ho - Journal of the American College …, 2023 - Elsevier
The incidence and prevalence of heart failure with preserved ejection fraction (HFpEF)
continue to rise in tandem with the increasing age and burdens of obesity, sedentariness …

Epidemiology of heart failure

A Groenewegen, FH Rutten, A Mosterd… - European journal of …, 2020 - Wiley Online Library
The heart failure syndrome has first been described as an emerging epidemic about 25
years ago. Today, because of a growing and ageing population, the total number of heart …

JCS/JHFS 2021 guideline focused update on diagnosis and treatment of acute and chronic heart failure

H Tsutsui, T Ide, H Ito, Y Kihara, K Kinugawa… - Circulation …, 2021 - jstage.jst.go.jp
After the publication of the revised edition, therapeutic drugs described in “Future Treatment”
were approved and important evidence for pharmacologic therapy and nonpharmacologic …

Heart failure with reduced ejection fraction: a review

SP Murphy, NE Ibrahim, JL Januzzi - Jama, 2020 - jamanetwork.com
Importance Worldwide, the burden of heart failure has increased to an estimated 23 million
people, and approximately 50% of cases are HF with reduced ejection fraction (HFrEF) …

Obesity and heart failure with preserved ejection fraction: new insights and pathophysiological targets

BA Borlaug, MD Jensen, DW Kitzman… - Cardiovascular …, 2022 - academic.oup.com
Obesity and heart failure with preserved ejection fraction (HFpEF) represent two
intermingling epidemics driving perhaps the greatest unmet health problem in …

Mechanistic insights of empagliflozin in nondiabetic patients with HFrEF: from the EMPA-TROPISM study

JA Requena-Ibáñez, CG Santos-Gallego… - Heart Failure, 2021 - jacc.org
Objectives The goal of this study was to evaluate the effect of empagliflozin, in addition to
optimal medical treatment, on epicardial adipose tissue (EAT), interstitial myocardial fibrosis …

Sex differences in cardiometabolic disorders

E Gerdts, V Regitz-Zagrosek - Nature medicine, 2019 - nature.com
The prevalence of cardiometabolic disorders in both women and men has increased
worldwide and is linked to a rise in obesity and obesity-associated associated clustering of …

Epidemiology of heart failure with preserved ejection fraction

SM Dunlay, VL Roger, MM Redfield - Nature Reviews Cardiology, 2017 - nature.com
Heart failure (HF) with preserved ejection fraction (HFpEF) is a clinical syndrome associated
with poor quality of life, substantial health-care resource utilization, and premature mortality …

Cellular and molecular differences between HFpEF and HFrEF: a step ahead in an improved pathological understanding

SJ Simmonds, I Cuijpers, S Heymans, EAV Jones - Cells, 2020 - mdpi.com
Heart failure (HF) is the most rapidly growing cardiovascular health burden worldwide. HF
can be classified into three groups based on the percentage of the ejection fraction (EF) …

The association of obesity and cardiometabolic traits with incident HFpEF and HFrEF

N Savji, WC Meijers, TM Bartz, V Bhambhani… - JACC: Heart Failure, 2018 - jacc.org
Objectives: This study evaluated the associations of obesity and cardiometabolic traits with
incident heart failure with preserved versus reduced ejection fraction (HFpEF vs. HFrEF) …